Journal of Practical Oncology ›› 2025, Vol. 39 ›› Issue (3): 262-266.doi: 10.11904/j.issn.1002-3070.2025.03.013

• Review • Previous Articles    

Current status of radiotherapy resistance research in breast cancer

WU Dan, WANG Yihai   

  1. Breast Radiation Therapy Department,Affiliated Cancer Hospital of Xinjiang Medical University,Urumqi 830011,China
  • Received:2024-12-28 Revised:2025-05-09 Online:2025-06-28 Published:2025-07-02

Abstract: As a common malignant tumor,breast cancer is the main cause of cancer death in women.Radiotherapy(RT)is one of its main treatment methods for breast cancer.RT resistance refers to the resistance of tumor cells and tissues to the biological effects of RT.The occurrence of RT resistance is closely related to the recurrence,metastasis and prognosis deterioration of breast cancer.In recent years,RT resistance of breast cancer has become a core issue in the field of RT research.The aim of this article is to review the potential mechanisms,influencing factors and corresponding countermeasures of breast cancer RT resistance,and to provide new ideas for the implementating personalized precision medicine in clinical practice.

Key words: Breast cancer, Radiotherapy, Radiotherapy resistance

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