炎症反应驱动乳腺癌转移的研究进展

doi:10.11904/j.issn.1002-3070.2024.05.009

Abstract

Abstract: The biggest challenge of breast cancer treatment is metastasis and drug resistance.Breast cancer metastasis increases mortality and decreases the life quality of patients.At present,the mechanism of breast cancer metastasis is not completely understood,and the multi-step process of metastasis,namely metastasis cascade,is determined by the internal characteristics of tumor cells and tumor microenvironment.Among the factors driving breast cancer metastasis,the role of inflammatory reaction has gradually attracted attention.The inflammatory environment composed of immune cells,cytokines,chemokines,and growth factors has an important impact on the invasion and metastasis of cancer cells.By studying the interaction between inflammatory reaction,tumor cells and tumor microenvironment,it is expected to discover drug targets for the prevention and treatment of breast cancer metastasis.This article reviews the role of inflammation in the tumor microenvironment of breast cancer metastasis.

Key words: Breast cancer, Inflammatory response, Metastasis

CLC Number:

R737.9

LIU Dong, ZHANG Taijuan, DANG Jifeng. The research progress of inflammatory reaction driving breast cancer metastasis[J]. Journal of Practical Oncology, 2024, 38(5): 336-341.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2024.05.009

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2024/V38/I5/336

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The research progress of inflammatory reaction driving breast cancer metastasis

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