Abstract: Objective To study the clinical effect of bronchial artery infusion(BAI)chemotherapy combined with systemic chemotherapy for patient with advanced non-small cell lung cancer.Methods 138 cases with advanced non-small cell lung cancer were divided into two groups.70 cases(A group)received BAI chemotherapy conbimed with systemic chemotherapy.68 cases(B group)were treated with systemic chemotherapy alone.The same systemic chemotherapy was taken in the two groups.The clinical data were analyzed retrospectively.Results Short-term response rate(61.42%),time to progression(TTP)(125.23 days),half-year survival rate(94.29%)and 1-year survival rate(94.29%)in BAI chemotherapy group were significantly higher than those in control group(46.27%,85.94 days,82.35%,42.65% respectively).Conclusion BAI chemotherapy combined with systemic chemotherapy is helpful for patient with advanced non-small cell lung cancer to improve therapeutic effect,to prolong survival time and improve quality of life.

Key words: Advanced lung cancer, Interventional therapy, Chemotherapy