Abstract: Objective To study the feedback and attentance experiences in 73 malignant tumor patients treated with CIK(cytokine induced killer)cells.Method Peripheral blood mononuclear cell(PBMC)from 73 malignant tumor patients were separated and gathered by blood corpuscle separate machine.The PBMC were cultured and proliferate in vitro and finally transfused back to these patients.The therapeutic effects were evaluated,and the adverse reaction were investigated.Results The sleep quality,appetite,stamina,and mental status were improved in 51 patients with different degrees,while no significantly improvement was observed in the rest patients;Except three patients(4.1%)observed with low-grade fever reactions,adverse effect was not found in all other cases(95.9%).Conclusion The CIK cells therapy is a safe,effective and feasible approach with few adverse effects for treatment malignant tumor patients,and the living quality of patients can be improved with the nursing interference.Therefore,the CIK cell therapy may have good application prospects in adoptive immunotherapy of cancer.

Key words: Cytokine-induced killer cells(CIK cells), Malignant tumour, nursing care