Journal of Practical Oncology ›› 2024, Vol. 38 ›› Issue (2): 136-140.doi: 10.11904/j.issn.1002-3070.2024.02.009

• Review • Previous Articles    

Research progress in the effect of Hirsutine on antitumor

YU Dahai, WANG Zhanshi, ZHAO Lizhu   

  1. Harbin University of Commerce,School of Pharmacy,Harbin 150078,China
  • Received:2024-01-15 Revised:2024-03-15 Online:2024-04-28 Published:2024-07-12

Abstract: Hirsutine,an indole alkaloid extracted from the traditional Chinese herb Uncaria,has exhibits diverse pharmacological activities,including antihypotensive,antiinfective,and cardioprotection.In cervical cancer,breast cancer,colon cancer,and other malignant tumors,hirsutine has effects on anti-tumor by regulating cell apoptosis,immune regulation and other pathways,laying the foundation for the application of hirsutine in the field of cancer therapy.This article reviews relevant literature both domestically and internationally to elucidate the research progress of hirsutine in anti-tumor therapy,providing new ideas and strategies for cancer treatment.

Key words: Hirsutine, Antitumor, Mechanisms of action, Pharmacological effects

CLC Number: