Abstract: Objective To investigate the treatment pattern in patients with visceral organ metastatic breast cancer who having symptoms of brain or bone metastasis involved.Method The total dose of whole-brain radiotherapy were 45Gy and 40Gy,respectively.Ther bone radiotherapy were 33Gy and 40Gy,respectively.At the same time,chemotherapy were given with Paclitaxol 80mg/m²,d1、8、15,every 21 days as one cycle.The efficacy was evaluated every 2 cycles of chemotherapy according to WHO standard.Result The Objective efficacy of 4 patients were PR.The constricts symptoms of the CNS and pain of the bone were relieved.TTP of 4 patients were 9、5、6+ and 8.5 months,respectively. Conclusion Treatment pattern of concurrent chemoradiotherapy in visceral organ metastatic patients with having symptoms of brain or bone metastasis result in a effectiveness to reduce symptoms and improve QOL.

Key words: Advanced breast cancer, Concurrent chemoradiotherapy, Chemotherapy, Radiotherapy