Abstract: Esophageal cancer with eyeball metastasis is scarce,and the clinical diagnosis is based on ultrasound.The treatment method is surgical removal at present.Our focus is through other local or systemic treatment to protect eyeball,protect the integrity intact and facial appearance.One patient&apos|s clinical data with esophageal eyeball metastasis from the People′s Liberation Army Cancer Center of No.105 Hospital was included.The patient was completed “enucleation of the right side of eyeball” by ultrasound diagnosis.The Results of pathological suggested that poorly differentiated squamous cell carcinoma metastasis in the eye.Eyeball metastases′s operation was received a good recovery after 2 months and there was no recurrence.In the present paper,we discuss esophageal eyeball metastases clinical characteristics and Methods of diagnosis and treatment combined with the literature.

Key words: Esophageal cancer, Eyeball metastasis, Enucleation