Abstract: Objective Esophageal cancer is one of the most common malignant tumors of the digestive tract,and Hebei province is located in the high-incidence area of esophageal cancer.This study aims to analyze the latest epidemic trends and characteristics of esophageal cancer in Hebei province from 2011 to 2016. Methods Statistical analysis was performed on the incidence and death data of esophageal cancer in 27 tumor registries of Hebei province.The incidence and mortality were analyzed by urban and rural,gender,and age group.The age-standardized rate was calculated using China′s 2000 census population and Segi′s World population.The grey model was used to predict the mortality of Cixian and Shexian,where were high-incidence areas. Results A total of 14,905 cases of esophageal cancer and 9,933 deaths of esophageal cancer from 2011 to 2016 were reported in Hebei province.The crude incidence was 21.73/100,000 and the mortality was 14.48/100,000.The incidence and mortality of esophageal cancer were both higher in men than those in women,and higher in rural areas than those in urban areas.The incidence and mortality of esophageal cancer in Hebei province had a downward trend(P＜0.001).The incidence and mortality in the high-incidence areas of Cixian and Shexian showed a long-term downward trend.It was predicted that the mortality of esophageal cancer would continue to decline in the next ten years. Conclusion The incidence and mortality of esophageal cancer in Hebei province are steadily declining,but the disease burden is still heavy.The primary prevention,early detection and early treatment of esophageal cancer should pay more attention to rural residents and male population.

Key words: Esophageal cancer, High-incidence areas, Incidence, Mortality, Tumor registration