PRACTICAL ONCOLOGY JOURNAL ›› 2016, Vol. 30 ›› Issue (2): 172-175.doi: 10.11904/j.issn.1002-3070.2016.02.017

• Review • Previous Articles     Next Articles

Research progress of CD44v6 in non-small cell lung cancer

CHEN Minghui, CHEN Xijie, WANG Yan   

  1. Department of Respiratory Medicine,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China
  • Received:2016-01-05 Online:2016-04-28 Published:2016-04-28

Abstract: CD44 is a transmembrane glycoprotein,which is a family of highly specific single chain membrane surface glycoproteins by a single gene.CD44 is mainly involved in the specific adhesion between cells and cells,cells and matrix.CD44v6 is a member of the CD44 family,and its correlation with metastasis and prognosis of non small cell lung cancer(NSCLC)has become a hot research topic in recent years.The current research progress of CD44v6 and NSCLC are reviewed in this paper.

Key words: CD44v6, Non-small cell lung cancer, Literature review

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