人类表皮生长因子受体2阳性肿瘤靶向药物研究进展

doi:10.11904/j.issn.1002-3070.2016.03.015

Abstract

Abstract: Human epidermal growth factor receptor 2(HER-2)is one of the most thoroughly studied human proto-oncogene.In previous studies,overexpression of HER-2 was observed in breast,ovarian,gastric,and many other cancers,as a result,which became the ideal target of drug development.Compared with traditional chemotherapy drugs,targeted drugs and inhibitors could better improve the patients prognosis and survival rate,as well as the safety and efficacy.This paper summarizes the research status of HER-2 positive tumors targeted drugs and treatment progress,which can provide useful references for HER-2 drug development and clinical treatment.

Key words: Human epidermal growth factor receptor2, Tumorigenesis, Targeted drug

CLC Number:

R730.54

WANG Lin,MENG Xiangning. Research progress on targeted drugs of human epidermal growth factor receptor 2 positive tumours[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(3): 266-270.

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Research progress on targeted drugs of human epidermal growth factor receptor 2 positive tumours

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