Journal of Practical Oncology ›› 2019, Vol. 33 ›› Issue (6): 540-543.doi: 10.11904/j.issn.1002-3070.2019.06.012

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Two-way regulation of NKT cells on immune response to liver cancer

LI Susu1, ZHOU Chunxiang1,2   

  1. 1.Nanjing University of Chinese Medicine,Nanjing 210046,China;
    2. Nanjing BenQ Hospital
  • Received:2019-05-03 Revised:2019-06-12 Published:2019-12-28

Abstract: Natural killer T(NKT)cells are a special T lymphocytes subset,which is also natural immune lymphocytes in the liver.It can secrete a large number of cytokines involved in the immune regulation of liver cancer and play dual regulatory roles in the immune response such as the occurrence,development and metastasis of liver cancer.The dual regulation function of promoting tumor and anti-tumor is related to various factors.This paper summarizes the research progress of the two-way regulation mechanism of NKT cells on liver cancer immunity in recent years.

Key words: NKT cells, Liver cancer, Immune response, Bidirectional regulation, Research progress

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