Journal of Practical Oncology ›› 2022, Vol. 36 ›› Issue (4): 293-298.doi: 10.11904/j.issn.1002-3070.2022.04.001

• Cancer Surveillance •     Next Articles

Analysis of 10-year survival rate of liver cancer among residents in three cities of Liaoning province from 2000 to 2002

NA Jun1, AN Xiaoxia2, LI Xun3, ZHANG Weiwei4, MU Huijuan1, LI Yanxia1, PAN Guowei5, LIU Li1   

  1. 1. Institute of Chronic Diseases,Liaoning Provincial Center for Disease Control and Prevention,Shenyang 110005,China;
    2. Institute of Chronic Diseases,Benxi Center for Disease Control and Prevention;
    3. Institute of Chronic Diseases,Shenyang Center for Disease Control and Prevention;
    4. Institute of Chronic Diseases,Anshan Center for Disease Control and Prevention;
    5. School of public health,China Medical University
  • Received:2021-08-16 Revised:2022-06-07 Online:2022-08-28 Published:2022-08-29

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Abstract: Objective The aim of this study was to analyze the 10-year survival status and influence factors of liver cancer patients from urban residents in Liaoning province,and to provide basic data for evaluating the progress of liver cancer prevention and treatment.Methods A total of 337 hepatocellular carcinoma patients randomly selected from the tumor incidence report database in three cities of Liaoning province from 2000 to 2002 were actively followed up and information was collected.The observed survival rate(OSR)and median survival time(T50)were calculated by the life table method.The Ederer Ⅱ method was used to calculate the relative survival rate(RSR).The multivariate Cox model was used to analyze the factors affecting survival.Results The T50,10-year OSR and RSR of urban residents with liver cancer in Liaoning province were 7.33 months,4.15% and 5.17%,respectively.There were no significant differences in T50,10-year OSR and RSR between male and female liver cancer patients.The 10-year OSR and RSR of the ＜65 years old group were 5.73% and 6.35%,respectively,which were slightly higher than those of the 65-74 years old group(2.15% and 3.27%)and the ≥75 years old group(1.92% and 4.02%),but there was no statistical difference.The T50(7.68 months)in the < 65 years old group was significantly higher than that in the 65-74 years old group(6.89 months)and the ≥75 years old group(6.93 months)(W=5.837,P=0.016;W=8.00,P=0.005).The 10-year RSR trend of the ＜65 years old was significantly different from that of the 65-74 years old and the ＞75 years old(χ2=6.736,P＜0.05;χ2=5.992,P＜0.05).The trend of the 10-year survival curve in the stage Ⅰ-Ⅱ was significantly different from that of stage Ⅲ and Ⅳ(χ2=9.391,P＜0.05;χ2=25.475,P＜0.05).The trend of the 10-year RSR between the surgery group and the non-surgery group was significantly different(χ2=10.767,P＜0.05).The T50 of the surgery group was significantly higher than that of the non-surgery group(W=14.746,P＜0.001).The results of multivariate Cox model analysis showed that gender and clinical stage had significant effects on 10-year survival time of liver cancer.Conclusion The low rate of early detection and standardized diagnosis may be the main reason.why the 10-year relative survival rate of liver cancer among urban residents in Liaoning province is lower than that of developed countries in Asia and Europe,so improve the early detection rate of liver cancer,strengthening compliance with the standardized diagnosis and treatment,preventing hepatitis and cirrhosis are an important direction for liver cancer control and prevention.

Key words: Liver cancer, 10-year relative survival rate, Median survival time, Staging

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