Abstract:

Objective To explore the influence of renal insufficiency with microwave therapy in the treatment of liver cancer.Methods A retrospective clinical analysis with 80 patients who underwent microwave therapy of liver cancer,was performed from June 2012 to March 2014 in the department of hepatobiliary and pancreatic surgery,the Affiliated Tumor Hospital of Harbin Medical University.According to perioperative presence of renal insufficiency,we divided the patients into renal dysfunction group(A)(n=44)and normal renal function group(B)(n=36);Preoperative ALT,TBIL,BUN,intraoperative hypotension,intraoperative urinary volume,age,the distance between the tumor and the main vessels in the liver,postoperative microwave ablation time the differences of the risk factors,such as microwave ablation range and sex of the two groups were compared during microwave therapy.Results There was no statistical significant difference between the two groups on intraoperative urinary volume(P＞0.05);The preoperative ALT,TBIL,BUN,intraoperative hypotension,age,microwave ablation time,the distance between the tumor and the main vessels in the liver,scular microwave ablation range,sex of two groups showed statistical differences(P＜0.05).BUN with preoperative ALT,TBIL,preoperative BUN,intraoperative hypotension,age,the distance between the tumor and the main vessels in the liver,time of microwave ablation,microwave ablation range,sex influence factors were positively correlated(r=0.63,0.60,0.58,0.49,0.45,0.40,0.35,0.46,0.52,P＜0.05).Strength and influencing factors of BUN are the distance between the tumor and the main vessels in the liver,microwave ablation range,intraoperative hypotension,preoperative ALT,sex,preoperative TBIL,microwave ablation time,age,preoperative BUN(β=0.52,0.42,0.37,0.31,0.29,0.25,0.20,0.18,0.16,P＜0.05).Conclusion Microwave therapy leads to renal insufficiency in the treatment of liver cancer performs many aspects,including preoperative ALT,TBIL,preoperative preoperative BUN,intraoperative hypotension,age,the distance between the tumor and the main vessels in the liver,time of microwave ablation,microwave ablation range,sex,which is closely related to the factors affecting the risk of kidney.

Key words: Liver cancer, Microwave healing, Renal insufficiency, Risk factors