Abstract: Gastric cancer(GC)is a common malignant tumor of the digestive system,which is mainly treated by surgery.With the improvement of medical level,the survival rate of gastric cancer patients has improved compared with the past.Postoperative complications have also attracted people′s attention.Clinical practice has found that some patients with GC may develop cholecystolithiasis or cholecystitis after surgery,and some even require secondary surgery,which seriously affects the quality of patients′ life.At present,there is no unified consensus on the risk factors of cholecystolithiasis after GC surgery.The relatively clear factors include neural factors,the scope of gastrectomy,gastrointestinal hormones,gastrointestinal reconstruction and lymph node dissection.At present,there is no consensus on the prevention of cholecystolithiasis after GC surgery,especially whether preventive cholecystectomy is needed,which is also the focus of clinicians.This article reviews the risk factors of cholecystolithiasis after GC surgery and the latest preventive measures,hoping to help clinical work.

Key words: Postoperative gastric cancer, Cholecystolithiasis, Risk factors, Ursodeoxycholic acid