Abstract: Objective Analysis of breast cancer epidemiological characteristics of high-risk groups in urban women,which will provide a scientific basis for prevention and control of breast cancer.Methods 24016 urban women were screened for breast cancer based on the questionnaire survey,physical examination,Doppler ultrasound and molybdenum x-ray examination.The data of screening were systematic collected and analyzed.Results Among 24016 women,a total of 1890 women were evaluated as high-risk group by questionnaire survey in advance,of which 14 cases with breast cancer were screened out and the rate was 58.3/100000.In the process of univariate analysis,we founded that there was statistic difference for detectable rate of breast cancer in different drinking habit,psychological depression,age for menstruation,age at first birth,duration for breastfeeding,and family history of breast cancer.Multivariate analysis showed that the independent risk factors for breast cancer in this cohort were frequent alcohol consumption(OR=2.31,95%CI:1.53~4.17),psychological depression(OR=3.20,95%CI:1.20~8.34),duration for breastfeeding≤12 months(OR=2.49,95%CI:1.23~5.18),and family history of breast cancer.Conclusion Screening in high-risk groups is an efficient and economic way for screening of breast cancer.Women with frequent alcohol consumption,psychological depression,duration for breastfeeding≤12 months,and family history of breast cancer should be given special attention in the process of breast cancer screening.

Key words: Breast cancer, Screening, Risk factors