宫颈癌持续或复发患者个体化化疗研究

doi:10.11904/j.issn.1002-3070.2016.03.009

Abstract

Abstract: Objective To compare the curative effect of individual chemotherapy with routine chemotherapy in patients with cervical cancer recurrence or continuous after radiation and chemotherapy.Methods 60 patients with cervical cancer recurrence or continuous after radiation and chemotherapy,and hospitalized in JingZhou Center Hospital between January 2013 and December 2015 were selected.They were divided into experimental group and control group randomly.The individualized chemotherapy programs were made based on the results of genetic testing in experimental group(30 eases).Gemcitabine combined cisplatin chemotherapy were used in the control group(30 eases).Evaluated the clinical efficacy and toxicity the incidence of adverse reactions after 2 curative cycles.Results The RR and DCR were significantly higher in the research than in the control group(P＜0.05).Median progression-free survival of experimental group was 6.5 months,significantly higher than 2.9 months of control group(P＜0.01).Marrow suppression in control group was more serious than in experimental group(P＜0.05).And no significant difference was found between groups in other adverse reactions(P＞0.05).Conculsion Individual chemotherapy had a better clinical curative effect than routine chemotherapy in patients with cervical cancer recurrence or continuous after radiation and chemotherapy.

Key words: Cervical cancer, Individual chemotherapy, Tumor

CLC Number:

R737.33

HU Yue,TANG Dong. Research of individual chemotherapy in patients with cervical cancer recurrence or continuous after radiation and chemotherapy[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(3): 240-244.

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Research of individual chemotherapy in patients with cervical cancer recurrence or continuous after radiation and chemotherapy

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