PRACTICAL ONCOLOGY JOURNAL ›› 2018, Vol. 32 ›› Issue (4): 315-319.doi: 10.11904/j.issn.1002-3070.2018.04.006

• Clinical Research • Previous Articles     Next Articles

Prognostic factors of postoperative survival in patients with primary gastrointestinal malignant lymphoma and the predictive value of TNM staging for long-term survival

LIU Yu1,WANG Zian2   

  1. 1.Bengbu Medical College of Anhui Province,Bengbu 233030,China;
    2.Department of Oncology,First Affiliated Hospital of Bengbu Medical College
  • Received:2018-05-23 Online:2018-08-20 Published:2018-09-06

Abstract: Objective The aim of this study was to explore the prognostic factors of postoperative survival of patients with primary gastrointestinal malignant lymphoma and the predictive value of TNM staging for long-term survival. Methods A total of 102 patients with primary gastrointestinal malignant lymphoma admitted into our hospital were retrospectively analyzed.The survival and survival time of 5 years after operation were confirmed by telephone follow-up.Cox regression analysis was used to observe the survival factors of patients with primary gastrointestinal malignant lymphoma.The survival curve of Kaplan Meier was used to analyze the predictive value of TNM staging on survival time of patient. Results Among the 102 patients,61 survived and 41 died,accounting for 59.80% and 40.20%,respectively.There was no distant metastasis and TNM stage in the survival group.The proportion of stage I to stage II and Lugano was higher than that in the death group.The difference was statistically significant(P<0.05).The Cox regression analysis showed that the distant metastasis,TNM stage and Lugano staging were positively related to patient death(P<0.05).Using TNM staging in patients with stage Ⅰ,Ⅱ,Ⅲ and Ⅳ of 5 years survival rates were 54.10%,21.31%,16.39%,21.31%.Using of Lugano staging in patients with stage Ⅰ,Ⅱ,Ⅱ E and Ⅳ of 5 years survival rate were 52.46%,22.95%,13.11%,11.48%.The prediction of long-term survival rate by TN. Conclusion The factors affecting the long-term survival of patients with gastric malignant lymphoma include distant metastasis,TNM staging,and Lugano staging.Compared with Lugano staging,the predictive effect of TNM staging on the long term survival is more ideal.

Key words: Malignant lymphoma of the gastrointestinal tract, TNM staging, Survival curve, Influencing factors

CLC Number: