Journal of Practical Oncology ›› 2020, Vol. 34 ›› Issue (6): 571-575.doi: 10.11904/j.issn.1002-3070.2020.06.017

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The latest research progress of the correlation between exosomes and gynecological malignant tumor

SONG Jiayu, FENG Yue, WANG Zhao, ZHANG Yunyan   

  1. Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2020-03-15 Revised:2020-06-10 Online:2020-12-28 Published:2020-12-23

Abstract: Gynecological malignant tumors are malignant diseases that affect women′s health and reduce women′s quality of life.They are gradually becoming younger.Because the early clinical manifestations of most gynecological malignancies are not obvious,many patients have reached the mid-advanced stage at the time of treatment.In patients with gynecological malignant tumors,the 5-year survival rate after surgery is positively correlated with the time of the patient′s initial diagnosis,so early diagnosis and early treatment are particularly important.In recent years,a number of studies have shown that exosomes are actively involved in the occurrence,invasion,metastasis and immune response of gynecological malignant tumors.Therefore,exosomes provide new research ideas for the early diagnosis,treatment and prognosis of tumors.This article reviews exosomes as an early screening marker for gynecological malignancies and the development of antitumor drugs in the clinical treatment.

Key words: Exosomes, Gynecological malignant tumors, Diagnostic markers, Targeted therapy

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