Journal of Practical Oncology ›› 2021, Vol. 35 ›› Issue (1): 55-58.doi: 10.11904/j.issn.1002-3070.2021.01.011

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The relationship between biomarkers of head and neck squamous cell carcinoma and prognosis of immunotherapy

ZHANG Lu1,LU Jingyu2,LU Haijun3   

  1. 1.Qingdao University in Shandong Province,Qingdao 266071,China;
    2.Binzhou Medical University;
    3.The Affiliated Hospital of Qingdao University
  • Published:2021-01-30

Abstract: Head and neck squamous cell carcinoma(HNSCC)is the sixth most common malignant tumor in the world,with an annual incidence of more than 550,000 cases and 300,000 deaths.Smoking and drinking alcohol are the main risk factors.The treatment plan of HNSCC is mainly based on TNM staging and primary surgery with comprehensive therapy(radiotherapy,chemotherapy and biological therapy).For the treatment of HNSCC,the 5-year survival rate has not improved in recent years.Therefore,new treatment methods are needed to increase the survival rate and improve the quality of patient life.The current research hotspot is the widespread application of immunotherapy-based biological targeted therapy for HNSCC.This study aims to explore the relationship between biomarkers of HNSCC and prognosis of immunotherapy.

Key words: Head and neck squamous cell carcinoma(HNSCC), HPV, p16, EBV, Prognosis, Immunotherapy

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