In the Upper Yangtze Region, especially in Guizhou Province and its adjacent areas, the dolostones of the Loushanguan Group of Cambrian were deposited in a shallowwater setting from Middle to Late Cambrian with a thickness of more than 1 000 meters. From northwest to southeast, they gradually changed into openplatform limestones and shelf micrites with water gradually deepening. Because of the poorly developed fossils, it is difficult to make a detailed chronostratigraphic subdivision. The development of pseudomorphic halite crystal dolostones reflects that the water of the sedimentary environment was shallowing and the development of grain dolostones reflects that the water was deepening. These features show that sequence stratigraphic division can be done on this set of dolostones by the method from lithofacies succession to sedimentary facies succession, which represents the “sedimentary facies shifting under the framework of sea level changing”. Thicklybedded and poorly fossiliferous dolostones of the Loushanguan Group contrast sharply with the thinlybedded finegrained mixed deposits with trilobite fossils of the Douposi Formation, and they make up a secondorder sequence that can further be divided into seven thirdorder sequences in the study area. The finegrained deposits of the Douposi Formation represent the water deepening by the second order transgression, while the poor fossiliferous dolostones of the Loushanguan Group progradated from northwest to southeast and represented a water shoaling process by the second order regression. The second order sequence itself is an upward shoaling sedimentary facies succession. The facies succession fabric of the second order sequence is similar to that of the third order sequence, and the fabric of the latter is similar to those of the meterscale cyclic sequences of zonal tidal flat which are composed by lithofacies successions. The Loushanguan Group dolostones in the study area constitute a complex, regular and distinct stratigraphic framework. It reflects that there is some regularity in the evolutionary succession of the sediments and their distribution characters. Its palaeogeographic evolution is controlled by both the deepening of transgression and the shoaling of regression, and at the same time, is controlled by the deepening of water depth from northwest to southeast. The study results of the Loushanguan Group dolostones show that the core of sequence stratigraphy is the regularity represented by the evolutionary succession and the distribution pattern of the sediments, and making a stratigraphic division and correlation according to the regularity.