实用肿瘤学杂志 ›› 2015, Vol. 29 ›› Issue (3): 271-274.doi: 10.11904/j.issn.1002-3070.2015.03.018

• 综述 • 上一篇    下一篇

雷替曲塞在实体肿瘤中应用的研究进展

赵洪伟综述, 张玉宝审校   

  1. 哈尔滨医科大学附属肿瘤医院肝胆胰外科(哈尔滨 150081)
  • 收稿日期:2014-10-25 出版日期:2015-06-28 发布日期:2015-06-25
  • 通讯作者: 张玉宝 E-mail:zhyb88077@sina.com
  • 作者简介:赵洪伟,男,(1987-),硕士研究生,从事肝胆胰肿瘤的研究

The progression on exploratory development of raltitrexed in solid tumors

ZHAO Hongwei,ZHANG Yubao   

  1. Department of Hepatobiliary and Pancreatic Surgery,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China
  • Received:2014-10-25 Online:2015-06-28 Published:2015-06-25

摘要:

雷替曲塞单独或联合其他抗癌药物在各种实体肿瘤化疗中能够起到较好的作用。本文分析了近年来国内、外有关雷替曲塞在各种实体肿瘤中的研究进展,探索其抗肿瘤的作用和机制。雷替曲塞是一种具有良好抗癌作用的药物,随着研究的深入,将会在实体肿瘤的治疗中发挥更大的作用。

关键词: 雷替曲塞, 胸苷酸合酶抑制剂, 实体肿瘤

Abstract:

The single or combined administration of Raltitrexed with other anticancer drugs have showed prospective curative effects on solid tumor.This paper reviews the current research situation of Raltitrexed against malignant tumor and explores the possibilities for the efficacy and mechanism in treatment of malignant tumor.Raltitrexed is one kind of effective anti cancer drugs and plays a more and more important role in solid tumor therapy.

Key words: Raltitrexed, TS inhibitor, Solid tumor

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