实用肿瘤学杂志 ›› 2022, Vol. 36 ›› Issue (3): 245-249.doi: 10.11904/j.issn.1002-3070.2022.03.009

• 综述 • 上一篇    下一篇

植物花青素对肿瘤抑制作用的研究进展

于晓兰1,2, 刘艳3 综述, 刘家仁1,2 审校   

  1. 1.哈尔滨医科大学附属第四医院检验科(哈尔滨 150001);
    2.黑龙江龙卫精准医学检验中心;
    3.哈尔滨医科大学附属第四医院肿瘤科
  • 收稿日期:2021-08-07 修回日期:2022-02-07 出版日期:2022-06-28 发布日期:2022-06-28
  • 通讯作者: 刘家仁,E-mail:Jiarenliu@hrbmu.edu.cn
  • 作者简介:于晓兰,女,(1993-),硕士研究生,从事植物化学物在肿瘤治疗应用方面的研究。
  • 基金资助:
    哈尔滨市重点科技攻关项目(编号:2021ZSZZNS02);黑龙江省应用技术研究与开发计划项目重大项目(编号:GA17C011);吴阶平医学基金会临床科研专项资助基金(编号:320.6750.2020-19-21)

Research progress in the inhibitory effects of plant anthocyanins on tumors

YU Xiaolan1,2, LIU Yan3, LIU Jiaren1,2   

  1. 1. Department of Clinical Laboratory,The Forth Affiliated Hospital of Harbin Medical University,Harbin 150001,China;
    2. Heilongjiang Longwei Precision Medical Laboratory Center;
    3. Department of Oncology,The Forth Affiliated Hospital of Harbin Medical University
  • Received:2021-08-07 Revised:2022-02-07 Online:2022-06-28 Published:2022-06-28

摘要: 植物花青素是一类可溶于水的类黄酮,主要存在于各种蔬菜水果中。常见的植物花青素主要分为天竺葵色素(Pelargonidin)、芍药色素(Peonidin)、矢车菊色素(Cyanidin)、锦葵色素(Malvidin)、矮牵牛色素(Petunidin)、飞燕草色素(Delphinidin)六种;植物花青素分子中含有共轭双键体系,并含有碱性或酸性基团,因而具有抗氧化、抗炎、调节免疫、抗衰老和抑癌等生物学作用,尤其以抑癌作用最为突出。因此,本文将对植物花青素的抑癌作用及可能的机制进行综述。

关键词: 植物花青素, 抑癌作用, 机制

Abstract: Plant anthocyanins are a class of water-soluble flavonoids,which mainly found in various vegetables and fruits.Common plant anthocyanins are mainly divided into six species including pelargonidin,peonidin,cyanidin,malvidin,petunidin,and delphinidin;Because the phytocyanin molecules contain conjugated double bond systems with basic or acidic groups,they have biological effects such as anti-oxidation,anti-inflammation,immune regulation,anti-aging,and anti-cancer,especially for inhibitory effects of tumor.Therefore,this article will review tumor suppressive effects and possible mechanisms of plant anthocyanins.

Key words: Plant anthocyanin, Inhibitory effects of tumor, Mechanism

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