关键词: 孤立性肺结节, 计算机辅助诊断, 神经网络

Abstract: Objective To evaluate the significance of diagnosis of isolation pulmonary nodules(SPN)using computer-aided diagnosis(CAD).Method 193 cases with SPN(including 144 cases of malignant nodules and 49 cases of benign nodules)proved pathologically by CT-guided biopsy in this paper,and analyzed the characteristics.According to the pathology results,Compare the accuracy of the neural network and artificial diagnosis of two methods in SPN's diagnostic.Result The diagnosis accurancy of neural network model was 71.5%,and the accurancy of artificial diagnosis was 80.3%,Sensitivity was 84.0% and 91.0%,respectively,specificity was 34.7% and 49.0% respectively.Conclusion Computer-aided diagnosis has better diagnostic accuracy rate,and the sensitivity of artificial neural network was closed to physicians diagnosis.It has certain significance in SPN diagnosis,can be a good diagnostic value,but with less accuracy.So it cannot completely replace the artificial diagnosis,but can be used as auxiliary diagnostic.

Key words: Isolation pulmonary nodules(SPN), Computer-aided diagnosis(CAD), Artificial neural network