实用肿瘤学杂志 ›› 2013, Vol. 27 ›› Issue (5): 406-409.doi: 10.3969/j.issn.1002-3070.2013.05.005

• 论著 • 上一篇    下一篇

厦门市海沧区结直肠癌筛查结果分析

黄连江1,袁玉涛1,何,洁2,张,晶1,颜松龄3,李小华2,庄建民3,梁小亮1   

  1. 1.厦门市第二医院检验科(厦门 361021)
    2.厦门市第二医院消化内镜科
    3.厦门市第二医院普通外科
  • 收稿日期:2013-03-28 出版日期:2013-10-28 发布日期:2013-10-15
  • 通讯作者: 梁小亮,E-mail:xmeylxl@sina.com
  • 作者简介:黄连江,男,(1979-),学士,主管检验技师,从事慢性病流行病学调查与医院感染监测工作的研究
  • 基金资助:
    厦门市海沧区科技局科技基金项目(350205Z20084003)

Analysis of colorectal screening results in the Haicang district of Xiamen city

HUANG Lianjiang1,YUAN Yutao1,HE Jie2,ZHANG Jing1,YAN Songling3,LI Xiaohua2,ZHUANG Jianmin3,LIANG Xiaoliang1   

  1. 1.Department of Laboratory,No.2 Hospital Ximen,Xiamen 361021,China
    2.Department of Digestive Endoscopy,No.2 Hospital Ximen
    3.Department of General Surgery,No.2 Hospital Ximen
  • Received:2013-03-28 Online:2013-10-28 Published:2013-10-15

摘要: 目的通过分析厦门市海沧区结直肠癌的筛查结果,探索筛查的结直肠癌最佳方案,以期达到对结直肠肿瘤的早发现、早诊断和早治疗。方法 自2008年12月—2010年10月,采用中国癌症基金会推荐的结直肠癌筛查方案,对海沧区4个行政村40~74岁常住居民结合问卷调查和连续粪便隐血试验(Fecal occult blood test,FOBT)进行初筛,共8179人,实际接受筛查6380人。高危人群接受全结肠镜检查。结果 经问卷调查和FOBT检测,获得结直肠癌高危人群1035例。81.06%的高危者接受全结肠镜检查,结直肠癌和腺瘤息肉及其他病变检出率分别为1.67%和23.96%。问卷调查及FOBT均阳性者结直肠癌检出率显著高于单纯问卷调查阳性者或单纯FOBT阳性者(P<0.05);FOBT两次阳性者结直肠癌检出率显著高于FOBT阴性和FOBT单次阳性检出率(P<0.05)。FOBT检测阳性次数与结直肠癌检出率和腺瘤息肉及其他病变检出率呈线性关系(P<0.05)。结论 调查问卷和连续粪便隐血试验筛查可明显缩小高危人群,大大降低筛查的工作量。

关键词: 结直肠癌, 筛查, 粪便隐血试验, 问卷调查

Abstract: Objective We intend to explore the best solution of colorectal cancer screening to achieve early detect,early diagnosis and early therapy for colorectal neoplasm by analyzing the Results of colorectal screening in Haicang District of Xiamen City.Methods From Dec.2008 to Oct.2010,preliminary screening was carried out to the inhabitants arranging from 40 to 74 years old in 4 villases of Haicang District combining questionnaires and continuous fecal occult blood test(FOBT),which is recommended by Chinese Cancer Fundation.High risk people accepted complete colonoscopy.Total number is 8179 people,among which 6380 people actually received screening.Results 81.06 percent of 1035 high risk people obtained by questionnaires and FOBT accepted complete colonoscopy.Positive incidence of colorectal cancer,adenomatous polyps and other lesions were 1.67% and 23.96% respectively.Colorectal cancer detection rate was significantly higher in questionnaires and FOBT were both positive than in questionnaire or FOBT positive alone(P<0.05).Colorectal cancer detection rate was significantly higher in FOBT twice positive than in FOBT negative or FOBT once positive(P<0.05).Significant linear relationship was observed between times of detection rate in FOBT positive and colorectal cancer and adenomatous polyps and other lesions detection rate(P<0.05).Conclusion Combining questionnaires and continuous FOBT can significantly concentrate high-risk group colorectal cancer,therefore can greatly reduce the workload of screening.

Key words: Colorectal cancer, Screening, Fecal occult blood test, Questionnaire

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