Abstract: Objective The aim of this study is to summarize and discuss the Results of video-assisted thoracoscopic surgery(VATS)in 58 patients with thoracic tumors.Methods From July 2005 to June 2007, 58 patients with thoracic tumors underwent VATS for peripheral pulmonary nodules, leiomyoma of esophagus, mediastinal lymphadenectasis, malignant pleumal fluid, bronchogenic cyst, medi-astinal cyst, neurofibroma.Results All procedures were performed successfully under VATS except for 3 cases, who were converted to thoracotomy for lung cancer.There was no mortality or severe complication in this series.Conclusion VATS is a safe and effective technique in selected patients with thoracic lesions.The overall incidence of perioperative complication is low.VATS has obvious advantages in treatment of benign thoracic lesions, however, the indications should be selected carefully for malignant tumors.