实用肿瘤学杂志 ›› 2014, Vol. 28 ›› Issue (4): 382-384.doi: 10.11904/j.issn.1002-3070.2014.04.020

• 综述 • 上一篇    

EphB受体与肿瘤发生进展的关系

苑梁 于志伟 综述 李永民 审校   

  1. 哈尔滨医科大学附属肿瘤医院结直肠外科 (哈尔滨,150081)
  • 出版日期:2014-08-28 发布日期:2014-07-31
  • 作者简介:苑梁,男,(1987-),硕士研究生,从事野生型EphB6基因的过表达与大肠上皮细胞恶性转化之间关系的研究

The relationship between EphB receptor with the development of tumor

YUAN Liang, YU Zhiwei, LI Yongmin   

  1. 1Departmeng of Colorectal Surgery,The Affiliated Tumor Hospital of Harbin Medical University, Harbin 150081, China
  • Online:2014-08-28 Published:2014-07-31

摘要: 摘要目前,研究发现EphB受体在调控正常细胞形态、细胞粘附能力、迁移运动能力及血管生成中起重要作用,与正常细胞的多种生物学行为密切相关。还有研究发现,EphB受体的异常表达与多种肿瘤的发生发展有一定关系。但EphB受体的异常表达对肿瘤的具体作用及作用机制尚无明确报道。可见,EphB受体是肿瘤学中重要的研究方向,对EphB受体与肿瘤之间关系的精确把握可以更好的了解肿瘤的进展情况,为肿瘤的治疗与预防提供更多科学依据及手段。

关键词: EphB受体, 肿瘤, 异常表达

Abstract: AbstractCurrently, EphB receptor has been found that it is an important impact on the biological behavior of normal cells. In some studies, which plays an important role in the regulation of normal cell morphology, cell adhesion, migration and angiogenesis. Another, there is a certain relationship between abnormal expression of EphB receptor with a variety of tumor development. Visible, EphB receptor is important research direction in cancer studies, accurate grasp of the relationship between EphB receptor and rumor can better understand the progress of the tumor, and the means to provide more scientific basis for cancer treatment and prevention.

Key words: EphB receptor, Tumor, Abnormal expression

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