长链非编码RNA(lncRNA)在癌症中的作用

doi:10.11904/j.issn.1002-3070.2019.05.017

摘要/Abstract

摘要： lncRNA在癌症患者的肿瘤组织和体液中易于检测,当lncRNA作为生物标志物时可以辅助诊断和治疗多种癌症。通过实时荧光定量PCR等分子工具对lncRNA进行检测可以诊断癌症,lncRNA中的SNP也可以为患者的癌症风险进行预测,有些lncRNA已被作为治疗靶点来治疗癌症。因此lncRNA对癌症患者的诊断、治疗及预后都有重要作用。

关键词: 长链非编码RNA, 诊断, 治疗, 预后

Abstract: LncRNA is easy to detect in tumor tissues and body fluids of cancer patients.When lncRNA is used as a biomarker,it can help the diagnosis and treatment of a variety of cancers.Detection of lncRNA by molecular tools such as real-time PCR can diagnose cancer,and SNPs in lncRNA can also predict cancer risk in patients.Some lncRNAs have been used as therapeutic targets to treat cancer.Therefore,lncRNA plays an important role in the diagnosis,treatment and prognosis of cancer patients.

Key words: Long non coding RNA, Diagnosis, Therapy, Prognosis

中图分类号:

Q522

李思维 , 庞达. 长链非编码RNA(lncRNA)在癌症中的作用[J]. 实用肿瘤学杂志, 2019, 33(5): 471-475.

LI Siwei, PANG Da. Long non-coding RNA(lncRNA)role in cancer[J]. Journal of Practical Oncology, 2019, 33(5): 471-475.

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链接本文: http://journal09.magtechjournal.com/Jwk3_syzlxzz/CN/10.11904/j.issn.1002-3070.2019.05.017

http://journal09.magtechjournal.com/Jwk3_syzlxzz/CN/Y2019/V33/I5/471

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