PRACTICAL ONCOLOGY JOURNAL ›› 2014, Vol. 28 ›› Issue (6): 549-552.doi: 10.11904/j.issn.1002-3070.2014.06.014

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Study of cellular and sub-cellular organelles targets on cancer therapy

ZHANG Baihong1,YUE Hongyun2   

  1. 1.Department of Oncology,General Hospital of People′s Liberation Army,Lanzhou 730050,China;
    2.Department of Ophthalmology,General Hospital of People′s Liberation Army
  • Received:2014-07-23 Online:2014-12-28 Published:2015-01-08

Abstract:

Tumor cell type and sub-cellular organelle are potential targets for cancer therapy.These targets have cell types including tumor-initiating cells,cancer stem cells,circulating tumor cells,metastasis-initiating cells,bone marrow derived cells and stromal cells,as well as sub-cellular organelles including mitochondria,lysosome,endoplasmic reticulum,extracellular vesicles,centrosome and nucleolus.New targets should provide more targeted therapy and personalized therapy for patients with human cancers.

Key words: Cancer cells, Sub-cellular organelles, Therapeutic targets

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