细胞凋亡在原发性肝癌治疗中的作用研究进展

doi:10.11904/j.issn.1002-3070.2016.05.013

Abstract

Abstract: Hepatocellular carcinoma(HCC)is one of the commonest malignant tumors in China.The therapeutic effects of conventional therapies including surgery resection at early stage,chemotherapy or radiotherapy are greatly less than expected.One of the most possible reasons is the blockage of apoptosis in HCC cells.This review collects literatures about the studies on the roles of key signal pathways including RA,STAT3,PDT,p53,β-catenin,TRAIL,microRNA and RAS in HCC therapy.This study may contribute greatly to providing outline insights for using apoptosis induction in liver cancer therapy.We hope it can promote the development liver cancer therapy in China.

Key words: Apoptosis, HCC, Signal pathway, Target therapy

CLC Number:

R735.7

ZHAO Xiangxuan, WEN Feng, MAO Xiaonan, LU Zaiming. Study advances on the roles of apoptosis in hepatocellular carcinoma therapy[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(5): 448-452.

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Study advances on the roles of apoptosis in hepatocellular carcinoma therapy

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