ICAM-1在肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2018.01.016

Abstract

Abstract: Intercellular adhesion molecule(ICAM-1),also known as CD54,is a transmembrane glycoprotein of the immunoglobulin superfamily and involved in tumor cell immune regulation,angiogenesis,invasion and distant metastasis.Many studies from domestic and abroad have proved that ICAM-1 is highly expressed in a variety of malignant tumors,which promotes the occurrence,development and prognosis of tumor.ICAM-1 also plays an important role in predicting the chemosensitivity of individual tumors.Therefore,ICAM-1 may provide a reference for the diagnosis and treatment of malignant tumors.This article summarizes effects of ICAM-1 on malignant tumors in recent years.

Key words: ICAM-1, Tumor, Progress, Prognosis

CLC Number:

ZHUANG Minmin, ZHANG Yunyan. Research progress of intercellular adhesion molecule-1 in tumor[J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(1): 82-86.

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Research progress of intercellular adhesion molecule-1 in tumor

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