SNP对放射性肺损伤预测作用的研究进展

doi:10.11904/j.issn.1002-3070.2019.01.016

Abstract

Abstract: Radiotherapy is an important treatment for lung cancer.However,the radiation-induced lung injury(RILI)affects some patients and also affects the efficacy of treatment.Therefore,it is very important to identify high-risk patients who may have RILI and take action intervention or monitoring.Although the individual difference is often explained by clinical and dosimetric,genetic factors also influence the occurrence of RILI.Currently,there are reports on the relationship between single nucleotide polymorphism(SNP)and RILI.The SNP of these specific genes may become an important predictor of RILI,and thus reduce the incidence of radiation-induced lung injury.

Key words: Radiation-induced lung injury, Single nucleotide polymorphism, Lung cancer

CLC Number:

R734.2

HU Zhihui, ZHANG Jing. Research progress in the prediction of SNP on radiation-induced lung injury[J]. PRACTICAL ONCOLOGY JOURNAL, 2019, 33(1): 87-91.

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Research progress in the prediction of SNP on radiation-induced lung injury

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