1 郑荣寿,陈茹,韩冰峰,等.2022年中国恶性肿瘤流行情况分析[J].中华肿瘤杂志,2024,46(3):221-231. 2 Wang LF,Wu LP,Wen JD.LncRNA AC079630.4 expression associated with the progression and prognosis in lung cancer[J].Aging(Albany NY),2021,13(14):18658-18668. 3 Teng PC,Liang Y,Yarmishyn AA,et al.RNA modifications and epigenetics in modulation of lung cancer and pulmonary diseases[J].Int J Mol Sci,2021,22:10592. 4 Schaefer M,Kapoor U,Jantsch MF.Understanding RNA modifications:the promises and technological bottlenecks of the ′epitranscriptome′[J].Open Biol,2017,7(5):170077. 5 Gu C,Shi X,Dai C,et al.RNA m6A Modification in cancers:Molecular mechanisms and potential clinical applications[J].Innovation(Camb),2020,1(3):100066. 6 Deng LJ,Deng WQ,Fan SR,et al.m6A modification:recent advances,anticancer targeted drug discovery and beyond[J].Mol Cancer,2022,21(1):52. 7 Li Y,Su R,Deng X,et al.FTO in cancer:functions,molecular mechanisms,and therapeutic implications[J].Trends Cancer,2022,8(7):598-614. 8 Qu J,Yan H,Hou Y,et al.RNA demethylase ALKBH5 in cancer:from mechanisms to therapeutic potential[J].J Hematol Oncol,2022,15(1):8. 9 Shi H,Wei J,He C.Where,when,and how:context-dependent functions of RNA methylation writers,readers,and erasers[J].Mol Cell,2019,74(4):640-650. 10 Sheng Y,Wei J,Yu F,et al.A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex-mediated DNA replication[J].Blood,2021,138(26):2838-2852. 11 Li B,Zhu L,Lu C,et al.circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity[J].Nat Commun,2021,12(1):295. 12 Yin H,Chen L,Piao S,et al.M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 pathway[J].Cell Death Differ,2023,30(3):605-617. 13 Hu Z,Zhu L,Zhang Y,et al.N6-methyladenosine-induced SVIL antisense RNA 1 restrains lung adenocarcinoma cell proliferation by destabilizing E2F1[J].Bioengineered,2022,13:3093-3107. 14 Ning J,Wang F,Bu J,et al.Down-regulated m6A reader FTO destabilizes PHF1 that triggers enhanced stemness capacity and tumor progression in lung adenocarcinoma[J].Cell Death Discov,2022,8(1):354. 15 Liu XS,Zhou LM,Yuan LL,et al.NPM1 Is a Prognostic biomarker involved in immune infiltration of lung adenocarcinoma and associated with m6a modification and glycolysis[J].Front Immunol,2021,12:724741. 16 Ma L,Xue X,Zhang X,et al.The essential roles of m(6)A RNA modification to stimulate ENO1-dependent glycolysis and tumorigenesis in lung adenocarcinoma[J].J Exp Clin Cancer Res,2022,41(1):36. 17 Xue L,Li J,Lin Y,et al.m6 A transferase METTL3-induced lncRNA ABHD11-AS1 promotes the Warburg effect of non-small-cell lung cancer[J].J Cell Physiol,2021,236(4):2649-2658. 18 Xu P,Hu K,Zhang P,et al.Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis[J].Cancer Cell Int,2022,22(1):13. 19 Wang N,Xu Y,Jin L,et al.Effects of N6-Methyladenosine Regulators on LAG3 and immune infiltrates in lung adenocarcinoma[J].Dis Markers,2022,2022:1829528. 20 Hu K,Yao L,Yan Y,et al.Comprehensive analysis of YTH domain family in lung adenocarcinoma:expression profile,association with prognostic value,and immune infiltration[J].Dis Markers,2021,2021:2789481. 21 Wu L,Cheng D,Yang X,et al.M2-TAMs promote immunoresistance in lung adenocarcinoma by enhancing METTL3-mediated m6A methylation[J].Ann Transl Med,2022,10(24):1380. 22 Shi CY,Yu CH,Yu WY,et al.Gut-Lung microbiota in chronic pulmonary diseases:evolution,pathogenesis,and therapeutics[J].Can J Infect Dis Med Microbiol,2021,2021:9278441. 23 Li Y,Gu J,Xu F,et al.Molecular characterization,biological function,tumor microenvironment association and clinical significance of m6A regulators in lung adenocarcinoma[J].Brief Bioinform,2021,22(4):225. 24 Guo W,Huai Q,Zhang G,et al.Elevated heterogeneous nuclear ribonucleoprotein C expression correlates with poor prognosis in patients with surgically resected lung adenocarcinoma[J].Front Oncol,2020,10:598437. 25 Guo W,Huai Q,Wan H,et al.Prognostic impact of IGF2BP3 expression in patients with surgically resected lung adenocarcinoma[J].DNA Cell Biol,2021,40(2):316-331. 26 Xiao H,Zhao R,Meng W,et al.Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer[J].J Pharm Anal,2023,13(6):625-639. 27 Chen B,Ye F,Yu L,et al.Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor[J].J Am Chem Soc,2012,134(43):17963-17971. 28 Huang Y,Yan J,Li Q,et al.Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5[J].Nucleic Acids Res,2015,43(1):373-384. 29 Chen WW,Qi JW,Hang Y,et al.Simvastatin is beneficial to lung cancer progression by inducing METTL3-induced m6A modification on EZH2 mRNA[J].Eur Rev Med Pharmacol Sci,2020,24(8):4263-4270. 30 Choe J,Lin S,Zhang W,et al.mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis[J].Nature,2018,561(7724):556-560. 31 Lin S,Liu Q,Lelyveld VS,et al.Mettl1/Wdr4-Mediated m7G tRNA Methylome is required for normal mrna translation and embryonic stem cell self-renewal and differentiation[J].Mol Cell,2018,71(2):244-255. 32 Balzeau J,Menezes MR,Cao S,et al.The LIN28/let-7 Pathway in Cancer[J].Front Genet,2017,8:31. 33 Ma J,Han H,Huang Y,et al.METTL1/WDR4-mediated m7G tRNA modifications and m7G codon usage promote mRNA translation and lung cancer progression[J].Mol Ther,2021,29(12):3422-3435. 34 Wang G,Zhao M,Li J,et al.m7G-Associated subtypes,tumor microenvironment,and validation of prognostic signature in lung adenocarcinoma[J].Front Genet,2022,13:954840. 35 Zhang C,Zhou D,Wang Z,et al.Risk model and immune signature of m7G-Related lncRNA based on lung adenocarcinoma[J].Front Genet,2022,13:907754. 36 Huang W,Qi CB,Lv SW,et al.Determination of DNA and RNA methylation in circulating tumor cells by mass spectrometry[J].Anal Chem,2016,88(2):1378-1384. 37 Li M,Tao Z,Zhao Y,et al.5-methylcytosine RNA methyltransferases and their potential roles in cancer[J].J Transl Med,2022,20(1):214. 38 Wang Y,Wei J,Feng L,et al.Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer[J].Mol Cancer,2023,22(1):81. 39 Chen Z,Qi M,Shen B,et al.Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs[J].Nucleic Acids Res,2019,47(5):2533-2545. 40 Tasaki M,Shimada K,Kimura H,et al.ALKBH3,a human AlkB homologue,contributes to cell survival in human non-small-cell lung cancer[J].Br J Cancer,2011,104(4):700-706. |