Journal of Practical Oncology ›› 2024, Vol. 38 ›› Issue (6): 421-426.doi: 10.11904/j.issn.1002-3070.2024.06.011

• Review • Previous Articles    

Research progress of RNA methylation in lung cancer

CHEN Xingyan1, LI Xue1, FU Qiang2   

  1. 1. Graduate School,Heilongjiang University of Chinese Medicine,Harbin 150040,China;
    2. School of Basic Medical Sciences,Heilongjiang University of Chinese Medicine
  • Received:2024-04-26 Revised:2024-10-23 Online:2024-12-28 Published:2025-01-06

Abstract: Lung cancer is one of the most common cancers.Although there has been a significant improvement in our understanding the risk,development,immune control,and treatment options of lung cancer,the limited understanding of its pathogenesis has resulted in insufficient targeted treatment strategies.In recent years,RNA methylation has become a research hot topic in the field of epigenetics,and proteins regulating RNA methylation have become important targets for cancer treatment.At present,some studies have reported the relationship between RNA methylation and biological processes such as oncogene expression,glycolysis,and immune response in lung cancer,but there is still no in-depth research and analysis.This article will start with the relationship between RNA methylation and lung cancer,explore the association between RNA methylation and the pathogenesis of lung cancer based on existing research,and discuss its future development direction.

Key words: Lung cancer, M6A methylation, N7-methylguanosine, 5-methylcytosine, N1-methyladenosine

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