盆腔肿瘤IMRT下骨髓剂量-体积参数与急性血液学毒性相关性研究进展

doi:10.11904/j.issn.1002-3070.2019.04.014

Abstract

Abstract: There is a high risk of myelosuppression in pelvic malignant tumors during concurrent chemoradiotherapy.The dose-volume relationship of pelvic exposed bone marrow(bone)is related to acute hematological toxicity during radiotherapy and chemotherapy,but lacks recognized parameters in this respect.The hematopoietic capacity of the bone marrow(bone)in different parts of the pelvic cavity is heterogeneous,and the pelvic bone marrow near the central axis has the strongest hematopoietic capacity,namely functional bone marrow.The relationship between dose-volume parameters of pelvic functional bone marrow and acute hematologic toxicity during chemoradiotherapy of pelvic malignant tumors may be the future direction.

Key words: Pelvic malignant tumors, Radiotherapy, Myelosuppression, Functional bone marrow, Dose-volume

CLC Number:

R730.55

CHEN Hongbo, YU Zengrong, DING Xiaofan, XIAO Lin. Progress of correlation between bone marrow dose-volume parameters and acute hematologic toxicity in pelvic malignant tumor[J]. Journal of Practical Oncology, 2019, 33(4): 361-366.

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Progress of correlation between bone marrow dose-volume parameters and acute hematologic toxicity in pelvic malignant tumor

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