Journal of Practical Oncology ›› 2019, Vol. 33 ›› Issue (4): 376-379.doi: 10.11904/j.issn.1002-3070.2019.04.017

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Advances in research on treatment of aberrant crypt foci

FANG Xuan, CHEN Hongsheng, Li Guodong, LIU Ming   

  1. Bio-Bank of Department of General Surgery,The Fourth Affiliated Hospital of Harbin Medical University,Harbin 150001,China
  • Received:2019-01-27 Published:2019-08-30

Abstract: Aberrant crypt foci(ACF)is highly similar to colorectal cancer(CRC)in phenotypic and molecular changes,and is positively correlated with the risk of CRC.It is considered as precancerous lesion of CRC.Many compounds have therapeutic effects on ACF,inhibiting their occurrence and malignant transformation,which can be regarded as a preventive effect on CRC.In this paper,we will review the treatment of ACF by various compounds in different ways in recent years.

Key words: Aberrant crypt foci, Treatment, Colorectal cancer

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