Abstract: Objective To estimate the morbidity and mortality of cancer and its epidemic characteristics in Jiangsu,2016. Methods Registration data in 2016 from 41 registries in Jiangsu was qualified after assessment and accepted as pooled data for final analysis by Jiangsu Provincial Center for Disease Control and Prevention in 2019.Stratified by areas(urban or rural),gender,age group and cancer sites,the incidence/mortality rates of pooled registration data were calculated,respectively.Combined with the provincial population data in 2016,new cancer cases and deaths in Jiangsu were estimated.And the crude incidence/mortality rates,age-standardized incidence/mortality rates by Chinese standard population,age-standardized incidence/mortality rates by World standard population,cumulative incidence/mortality rate(0~74 years old)and the rank of 10 leading cancers were calculated,respectively.Chinese population census in 2000 and World Segi's standard population were used for age-standardized. Results It was estimated that there were 254.1 thousands new cancer cases in Jiangsu in 2016,with a crude incidence rate of 327.48/100,000,age-standardized incidence rate by Chinese standard population(ASR China)of 182.61/100,000,age-standardized incidence rate by World Segi's standard population(ASR world)of 178.85/100,000 and a cumulative incidence rate of 20.98% for 0~74 years.Cancers of lung,stomach,esophagus,colorectum,liver and female breast were the most common cancer in Jiangsu.The estimated number of deaths for malignant tumor was 168.7 thousand in Jiangsu in 2016,with a crude mortality rate of 217.44/100,000,ASR China mortality of 109.30/100,000,ASR World mortality of 107.94/100,000 and a cumulative mortality rate of 12.15% for 0~74 years.Lung cancer,stomach cancer,esophageal cancer,liver cancer and colorectal cancer were the most common causes of cancer related death in Jiangsu.It was estimated that more than 81% of new cancer cases and over 91% of cancer deaths in Jiangsu occurred in the population aged 50 years and older,particularly in the population aged 60 years and older. Conclusion The burden of cancer showed a continuous upward trend in Jiangsu,with a cancer pattern of presenting the coexistence of the cancer patterns in developed and developing countries.In order to reduce the mortality of cancer,comprehensive cancer prevention and control program should be implemented based on the specific situation in different areas and different cancer sites.

Key words: Cancer registry, Malignant tumor, Incidence, Mortality, Jiangsu