Abstract: Objective The aim of this study was to analyze the prevalence of malignant tumors in Qionghai city cancer registration areas from 2010 to 2016,and to provide scientific basis for the formulation of tumor prevention strategies and measures in Qionghai city. Methods The tumor incidence and death cases reported by the Qionghai Cancer Registry from 2010 to 2016 were collected.The crude incidence(mortality)of malignant tumors,the China standard rate,the World standard rate,the age-specific incidence(mortality),the cumulative rate(0~74 years old)were calculated.The China standard rate and World standard rate were calculated using the standard age composition of China's standard population in 2000 and Segi's standard population,respectively.The Joinpoint regression was used to analyze the trend of malignant tumor incidence and mortality of different years old groups. Results A total of 7,119 new malignant tumor cases were collected in Qionghai city from 2010 to 2016,with an average incidence of 204.63/100,000(the China standard rate was 155.16/100,000,the World standard rate was 155.16/100,000),and the cumulative rate(0~74 years old)was 17.26%.The average incidence for male was 232.97/100,000(the China standard rate was 172.64/100,000,the World standard rate was 78.95/100,000),which was higher than female 173.02/100,000(the China standard rate was 134.90/100,000,the World standard rate was 125.27/100,000).The top 5 malignant tumors in the overall population were lung cancer,liver cancer,colorectal cancer,stomach cancer and cervix cancer.A total of 4,787 deaths from malignant tumors were collected from 2010 to 2016,with an average mortality of 140.23/100,000(the China standard rate was 102.70/100,000,the World standard rate was 101.18/100,000).The cumulative rate of 0~74 years old was 11.69%.The average mortality for male was 176.50/100,000(the China standard rate was 128.10/100,000,the world standard rate was 133.33/100,000),which is higher than female 99.74/100,000(the China standard rate was 74.10/100,000,the World standard rate was 69.42/100,000).The top 5 malignant tumors in the total population were lung cancer,liver cancer,colorectal cancer,stomach cancer and breast cancer.The Joinpoint model analysis showed that the incidence of malignant tumors showed a downward trend from 2010 to 2012,and the difference was not statistically significant(P＞0.05),while it showed a significant upward trend from 2012 to 2016,with an average annual increase of 8.9% in the incidence of malignant tumors,which was statistically significant difference(P＜0.05).The mortality of malignant tumors had been increasing year by year from 2010 to 2016,but the difference was not statistically significant(P＞0.05). Conclusion The incidence and mortality of malignant tumors in Qionghai city continued to increase from 2010 to 2016.There is a burden of coexistence of cancer in developed and underdeveloped areas.The early screening and diagnosis of important cancers such as breast cancer,cervical cancer and liver cancer should be strengthened.

Key words: Cancer registration, Malignant tumor, Incidence, Mortality