香叶醇抗肿瘤活性及其他生物学作用的研究进展

doi:10.11904/j.issn.1002-3070.2023.01.010

Abstract

Abstract: Geraniol(GI)is an acyclic isoprenoid monoterpene isolated from the essential oils of aromatic plants.So far,a number of experimental evidence has demonstrated that GI has various activities,such as anti-tumor,anti-inflammatory,antioxidant and antibacterial activities,as well as liver protection,heart protection and neuroprotection.GI has therapeutic or preventive effects on different types of tumor,and the mechanism basis of its pharmacological action has been revealed.In addition,GI enhances the sensitivity of tumor cells to commonly used chemotherapy drugs.GI controls a variety of signaling molecules and pathways that represent tumor characteristics.These effects of GI limit the ability of tumor cells to acquire adaptive resistance to antitumor drugs.Thus,the above studies indicate that GI can be used as a promising bioactive compound to treat or prevent chronicle diseases.This article reviews the research progress of GI in anti-tumor and other biological effects.

Key words: Geraniol, Anti-tumor activity, Biological functions

CLC Number:

CAI Qirui, YU Xiaolan, LIU Jiaren. Research progress on antitumor activity and other biological effects of geraniol[J]. Journal of Practical Oncology, 2023, 37(1): 58-62.

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Research progress on antitumor activity and other biological effects of geraniol

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