术前血清甲状腺球蛋白检测对甲状腺乳头状癌颈部淋巴结转移的预测价值分析

doi:10.11904/j.issn.1002-3070.2023.01.009

Abstract

Abstract: Objective The Objective of this study was to investigate the relationship between preoperative serum thyroglobulin(PS-Tg)and lymph node metastasis(LNM)in papillary thyroid carcinoma(PTC). Methods This study included 283 clinical and pathological data of PTC patients who underwent thyroidectomy from October 2021 to September 2022 and were confirmed by postoperative pathology.The relationship between PS-Tg and PTC LNM was analyzed by univariable and multivariable logistic regression,the nomogram was used to quantify the relationship between them,and the optimal cut-off value was determined by receiver operating characteristic(ROC)curves. Results The level of PS-Tg in the PTC combined with LNM group was higher than that in the pure PTC group(P＜0.05).Univariable and multivariable logistic regression analyses showed that elevated PS-Tg level might be an independent risk factor for LNM of PTC,and the increase of PS-Tg level could explain approximately 15% of the risk of LNM in PTC. Conclusion Elevated PS-Tg level may be a risk factor for cervical LNM in PTC patients,and it has a certain predictive value for preoperative LNM diagnosis.

Key words: Papillary thyroid carcinoma, Lymph node metastasis, Preoperative serum thyroglobulin

CLC Number:

R736.1

WANG Yiying, KONG Wei, LIU Qinghua, XING Hao, YIN Fengyan, LIU Xinyue, HE Qian, XING Weijia. Analysis for predictive value of preoperative serum thyroglobulin detection in cervical lymph node metastasis of thyroid papillary carcinoma[J]. Journal of Practical Oncology, 2023, 37(1): 52-57.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2023.01.009

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2023/V37/I1/52

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Analysis for predictive value of preoperative serum thyroglobulin detection in cervical lymph node metastasis of thyroid papillary carcinoma

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