Abstract: Lung cancer is the second most common cancer worldwide after breast cancer,due to increasing morbidity and mortality from diseases related to smoking,air pollution and lung infections,as well as increasing awareness of cancer screening.However,due to the lack of obvious clinical features of early-stage lung cancer,most patients are diagnosed at an advanced stage.Therefore,the early and accurate diagnosis of benign and malignant pulmonary lesions is very necessary for the treatment and prognosis of patients.Peripheral pulmonary lesions(PPLs)are located in a special location,close to or even close to the chest wall,which enables ultrasound to break the “taboo” of lung examination and exert its unique advantages.With the continuous development of ultrasound technology,multimodal ultrasound diagnosis technology has been gradually applied to the examination of PPLs to improve the accuracy of disease diagnosis.This article will review the application progress of multimodal ultrasound in the diagnosis of benign and malignant peripheral pulmonary lesions.

Key words: Peripheral pulmonary disease, Lung cancer, Multimodal ultrasound, Contrast-enhanced ultrasound, Ultrasound elastography