化疗联合腹腔循环热灌注治疗恶性腹水疗效和安全性的Meta分析

doi:10.11904/j.issn.1002-3070.2016.04.013

Abstract

Abstract: Objective To evaluate the clinical efficacy and safety of celiac continued circulatory hyperthermia perfusion with chemotherapy in the treatment of cancer with ascites.Methods Databases including the Cochrane Library MEDLINE,PubMed,Embase,CBM,VIP,CNKI and WanFang Data,and the other sources as supplying.The literatures were screened according to the inclusion criteria,extracted data and assessed the methodological quality,and then meta-analysis was performed using RevMan 5.0.2 software.Results Totally 14 RCTs with 867 patients were included.Meta-analysis showed that compared intraperitoneal chemotherapy,with celiac continued circulatory hyperthermia perfusion had a significant difference in CR(OR=3.18,95%CI:2.18~4.64,P＜0.00001),PR(OR=2.05,95%CI:1.51~2.77,P＜0.00001),overall effective rate(OR=4.88,95%CI:3.59~6.46,P＜0.00001).The incidence of adverse reactions was no statistically significant in the two groups.Conclusion Celiac continued circulatory hyperthermia perfusion with chemotherapy in the treatment of cancer with ascites demonstrates better efficacy and safety,but it still needs to verify the above conclusion.

Key words: Malignant ascites, Chemotherapy, Celiac continued circulatory hyperthermia perfusion, Meta-analysis

CLC Number:

R730.58

YAN Xiangyong ,YAN Zhongsheng ,LIU Wenchao ,DING Hui. Effect and safety of celiac continued circulatory hyperthermia perfusion with chemotherapy in the treatment of cancer with ascites Meta-analysis[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(4): 356-364.

References

1 Woopen H,Sehouli J.Current and future options in the treatment of malignant ascites in ovarian cancer[J].Anticancer Res,2009,29(8):3353-3359.
2 Ba MC,Cui SZ,Lin SQ,et al.Chemotherapy with laparoscope-assisted continuous circulatory hyperthermic intraperitoneal perfusion for malignant ascites[J].World J Gastroenterol,2010,16(15):1901-1907.
3 Di Giorgio A,Naticchioni E,Biacchi D,et al.Cytoreductive surgery(peritonectomy procedures)combined with hyperthermic intraperitoneal chemotherapy(HIPEC)in the treatment of diffuse peritoneal carcinomatosis from ovarian cancer[J].Cancer,2008,113(2):315-325.
4 Gesson-Paute A,Ferron G,Thomas F,et al.Pharmacokinetics of oxaliplatin during open versus laparoscopically assisted heated intraoperative intraperitoneal chemotherapy(HIPEC):an experimental study[J].Ann Surg Oncol,2008,15(1):339-344.
5 杨纪华,闵婕,李伟民,等.循环热灌注化疗治疗恶性腹腔积液疗效观察[J].现代肿瘤医学,2009,17(11):2185-2187.
6 胡宗兰,曹军丽,顾涛,等.腹腔热灌注联合全身化疗在卵巢癌恶性腹腔积液控制中的近期疗效[J].山东医药,2009,49(40):42-43.
7 蒋冬梅,闫明亮,张海亮,等.腹腔持续循环热灌注化疗治疗癌性腹腔积液的临床研究[J].陕西医学杂志,2010,39(1):42-44.
8 陈非,郭黔,罗舒,等.腹腔热灌注联合全身化疗治疗恶性腹腔积液的疗效观察[J].重庆医学,2011,40(34):3465-3466.
9 廖国清,曲怡梅,王红梅,等.循环热灌注化疗治疗晚期胃癌合并腹腔积液的临床研究[J].中国肿瘤临床,2012,39(8):452-454.
10 吴铁鹰,张峻青,刘永兰,等.腹腔循环热灌注化疗治疗恶性腹腔积液疗效观察[J].肿瘤研究与临床,2013,7(9):202-203.
11 李维,王华庆,赵阔,等.奈达铂腹腔热灌注化疗治疗癌性腹腔积液的疗效观察及分析[J].中国肿瘤临床,2012,39(22):1741-1744.
12 李娜,薄常文,邹长鹏,等.循环热灌注化疗与单纯灌注化疗治疗胃肠道肿瘤恶性腹腔积液的疗效比较[J].世界华人消化杂志,2013,21(33):3757-3761.
13 张立新,孙芳初,孙国贵,等.顺铂联合腹腔持续热灌注治疗胃癌腹腔转移癌性腹水的临床研究[J].中国肿瘤,2013,22(5):413-416.
14 王红梅,廖国清,邵艳,等.替吉奥联合顺铂腹腔热灌注化疗治疗晚期结直肠癌合并腹腔积液48例疗效观察[J].贵州医药,2014,22(27):23-24.
15 孙玉芬.腹腔热灌注联合全身化疗治疗卵巢癌恶性腹腔积液的近期疗效[J].中国肿瘤临床与康复,2013,20(4):369-370.
16 覃振赫.腹腔恒温循环热灌注化疗治疗癌性腹水的疗效[J].华夏医学,2013,26(3):504-506.
17 李涛,吴祥成,吴非常,等.多西他赛联合腹腔热灌注顺铂治疗卵巢癌腹腔积液18例[J].社区医学杂志,2013,11(11):47-48.
18 彭定宏,袁静,曹付梅.腹腔循环热灌注联合静脉化疗在胃癌合并腹腔积液的应用[J].中国实用医药,2014,9(7):166-167.
19 Fujimoto S,Shrestha RD,Kokubun M,et al.Intraperitoneal hypertheric perfusion combined with surgery effective for gastric cancer patients with peritoneal seeding[J].Ann Surg,1988,208(1):36-41.
20 Qian J,Truebenbach J,Graeple F,et al.Application of polylactide-co-glycolide -microspheres in the transarterial chemoembolization in an animal model of HCC[J].World J Gastroenterol,2003,9(1):94-98.

[1]	LIANG Hong, LI Qi, WANG Yaoxian, JIN Hong, WANG Tong, WANG Yanan, DUAN Yani, SONG Min. Interrupted time series trial for prevention of cardiovascular toxicity induced by chemotherapy in cervical cancer [J]. PRACTICAL ONCOLOGY JOURNAL, 2019, 33(2): 134-138.
[2]	MA Zhijie, WANG Fan, ZHAO Yashuang. Analysis of life quality and influencing factors in breast cancer patients with chemotherapy [J]. PRACTICAL ONCOLOGY JOURNAL, 2019, 33(2): 149-154.
[3]	QIN Lanqun, ZOU Zhengyun. Progress in chemotherapy for malignant melanoma [J]. PRACTICAL ONCOLOGY JOURNAL, 2019, 33(2): 167-172.
[4]	CHANG Xiaoxia, SONG Bingbing, LIU Jiaren. Research progress in phytochemicals for increasing sensitivity of tumor cells to chemotherapies [J]. PRACTICAL ONCOLOGY JOURNAL, 2019, 33(1): 67-72.
[5]	WANG Yalong, LYU Zhangyan, ZHANG Fan, FENG Xiaoshuang, WEI Luopei, LI Xin, WEN Yan, GAO Yushun, XUE Qi, GAO Shugeng, TAN Fengwei. Relationship between human papillomavirus infection and prognosis of lung cancer:A meta-analysis [J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(6): 520-526.
[6]	JIANG Liangliang, WANG Jing. Progress in diagnosis and treatment of distant metastasis of epithelial ovarian cancer [J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(5): 480-482.
[7]	ZHANG Ting, JIA Di, YANG Dan. Progress in biological treatment of osteosarcoma [J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(3): 254-257.
[8]	ZHAI Keke, GAO Yuanyuan, FENG Xiao, XU Jingwen, GONG Yufang, MENG Qingwei. Analysis of first-line NSCLC chemotherapy in the phase Ⅳ patients with distant metastasis and first diagnosis after postoperative adjuvant chemotherapy [J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(2): 107-111.
[9]	YANG Wenjuan, YU Jing, HUANG Zhao, ZHANG Junhong, XIE Conghua. Correlation between the decline of severe granulocyte in the early stage of chemotherapy and the prognosis of small cell lung cancer [J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(1): 19-24.
[10]	LI Yujiao, SHANG Naijian. Research progress of imaging evaluation of neoadjuvant chemotherapy in breast cancer [J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(1): 63-67.
[11]	LIANG Yusi, TAN Yonggang, ZOU Huawei. Research progress on mechanism of low-dose chemotherapy [J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(6): 538-542.
[12]	DONG Feng,MA Junjun,CAI Zhenghao,ZHAO Xuan,ZHENG Minhua. The correlation between serum miR-21 and miR-34a expression and the efficacy of Flofox chemotherapy regimen in patients with advanced gastric carcinoma [J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(2): 147-151.
[13]	CHEN Li, ZHANG Yuxin, ZUO Yanjiao, MA Fei, SONG Hongjiang, XUE Yingwei. The comparison of clinical efficacy of SOX and XELOX in the neoadjuvant chemotherapy for advanced gastric carcinoma [J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(1): 23-30.
[14]	ZHANG Rui,WANG Zhiyu,WANG Shuai,ZHAO Hui. Efficacy of recombinant human endostatin combined with vinorelbine-cisplatin regimen in newly diagnosed patients with advanced non-small cell lung cancer patients with bone metastases and the impact on expression of serum VEGF [J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(6): 527-522.
[15]	SUN Dawei,LEI Minghui. The study on immunity and tumor recurrence of oral cancer patients with the combination therapy of hyperbaric oxygen treatment and postoperative adjuvant chemotherapy [J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(6): 533-537.

Effect and safety of celiac continued circulatory hyperthermia perfusion with chemotherapy in the treatment of cancer with ascites Meta-analysis

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments