肠道上皮细胞再生修复与恶性转化的研究现状

doi:10.11904/j.issn.1002-3070.2017.03.015

Abstract

Abstract: Chronic inflammation of intestine mucosal has been considered as a critical component of colorectal cancer development.Recently,the studies based on high throughput sequencing of colorectal cancer patients released a potential molecular subtype of colorectal cancer,characterized by wound healing and innate immune genes.It suggests that a probably mechanism described by a subset of cells that may be dependent on inflammatory cells and cytokines of tumor development,extremely expanding our insight of cell malignant transformation,and highlight the anti-inflammation treatment.This article will review the normal mechanism of intestine mucosal renewal,wound healing and malignant transformation.

Key words: Intestine mucosal, Chronicinflammation, Malignant transformation

CLC Number:

R320.2710

JIANG Meng,LIU Ming. Self renewal,repair and malignant transformation of intestine epithelial cells[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(3): 262-267.

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Self renewal,repair and malignant transformation of intestine epithelial cells

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