功能磁共振成像在胶质瘤精确诊断中的研究

doi:10.11904/j.issn.1002-3070.2017.06.008

Abstract

Abstract: Objective The aim of this study was to evaluate the glioma using the variety of functional magnetic resonance imaging(fMRI),and to perform a more accurate preoperative diagnosis of gliomas.Methods Thirty-five patients with gliomas confirmed by pathology were examined by magnetic resonance imaging(MRI)and functional MRI.Rapid diffusion coefficient(D*),Slow diffusion coefficient(D),perfusion fraction(f)and distribution diffusion coefficient(DDC)in the intravoxel incoherent motion diffusion weighted imaging(IVIM-DWI)were analyzed statistically.Results The mean values of D*,D,f and DDC in the IVIM sequence of the patients with high-grade of gliomas were statistically significant when compared to the IVIM values of the contralateral normal brain tissues(P＜0.05).Conclusion A variety of magnetic resonance functional imaging sequences are used to analyze gliomas,which can avoid tumor heterogeneity and improve the recognition ability and accuracy of magnetic resonance imaging in high grade gliomas.

Key words: Gliomas, Magnetic resonance imaging, Intravoxel incoherent motion, Enhanced gradient echo T2 star weighted angiography, Arterial spin labeling.

CLC Number:

R445.2

WANG Wei, SUN Peng, LIU Yanshu, LI Lulu, LIU Zhilan, ZHANG Yuanli, ZHANG Yujing. Functional magnetic resonance imaging in the accurate diagnosis of gliomas[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(6): 524-527.

References

1 Mangla R,Ginat DT,Kamalian S,et al.Correlation between progression free survival and dynamic susceptibility contrast MRI perfusion in WHO grade III glioma subtypes[J].J Neurooncol,2014,116(2):325-331.
2 Hu YC,Yan LF,Wu L,et al.Intravoxel incoherent motion diffusion-weighted MR imaging of gliomas:efficacy in preoperative grading[J].Sci Rep,2014,4:7208.
3 Lin Y,Li J,Zhang Z,et al.Comparison of intravoxel incoherent motion diffusion-weighted MR imaging and arterial spin labeling MR imaging in gliomas[J].Biomed Res lnt,2015,2015:234-245.
4 Bai Y,Lin Y,Zhang W,et al.Noninvasive amide proton transfer magnetic resonance imaging in evaluating the grading and cellularity of gliomas[J].Oncotarget,2017,8(4):5834-5842.
5 Law M,Yang S,Wang H,et al.Glioma grading:sensitivity,specificity,and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging[J].AJNR Am J Neuroradiol,2003,24(10):1989-1998.
6 Shen N,Zhao L,Jiang J,et al.Intravoxel incoherent motion diffusion-weighted imaging analysis of diffusion and microperfusion in grading gliomas and comparison with arterial spin labeling for evaluation of tumor perfusion[J].J Magn Reson Imaging,2016,44(3):620.
7 Le BD,Breton E,Lallemand D,et al.Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging.[J].Radiology,1988,168(2):497-505.
8 Le BD,Breton E,Lallemand D,et al.MR imaging of intravoxel incoherent motions:application to diffusion and perfusion in neurologic disorders.[J].Radiology,1986,161(2):401-407.
9 Kim HS,Kim SY.A prospective study on the added value of pulsed arterial spin-labeling and apparent diffusion coefficients in the grading of gliomas.[J].AJNR Am J Neuroradiol,2007,28(9):1693-1699.
10 李锐,刘晋红,王玉林,等.三维动脉自旋标记与磁共振动态对比增强成像参数在胶质瘤术前分级中的对照研究[J].肿瘤影像学,2016,25(3):217-222.
11 Wong AM,Feng X Yan MS,et al.Comparison of three-dimensional pseudo-continuous arterial spin labeling perfusion imaging with gradient-echo and spin-echo dynamic susceptibility contrast MRI[J].J Magn Reson Imaging,2014,39(2):427-433.
12 Järnum H,Steffensen EG,Knutsson L,et al.Perfusion MRI of brain tumours:a comparative study of pseudo-continuous arterial spin labelling and dynamic susceptibility contrast imaging[J].Neuroradiology,2010,52(4):307-317.
13 Caulo M,Panara V,Tortora D,et al.Data-driven grading of brain gliomas:a multiparametric MR imaging study[J].Radiology,2014,272(2):494-503.
14 Furtner J,Bender B,Braun C,et al.Prognostic value of blood flow measurements using arterial spin labeling in gliomas[J].PLoS One,2014,9(6):e99616.
15 Di Ieva A,Matula C,Grizzi F,et al.Fractal analysis of the susceptibility weighted imaging patterns in malignant brain tumors during antiangiogenic treatment:technical report on four cases serially imaged by 7 T magnetic resonance during a period of four weeks[J].World Neuro Surg,2012,77(5/6):785.
16 Bai Y,Lin Y,Tian J,et al.Grading of gliomas by using monoexponential,biexponential,and stretched exponential diffusion-weighted MR imaging and diffusion kurtosis MR imaging[J].Radiology,2016,278(2):496-504.
17 Castillo M,Smith JK,Kwock L,et al.Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas[J].AJNR Am J Neuroradiol,2001,22(1):60-64.

[1]	ZHAO Yongrui, XU Jiankun. The application of PET/MRI in high-grade glioma by radiotherapy [J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(6): 564-568.
[2]	WANG Qifan, ZHANG Xiushi, YU Youtao, ZHANG Hongxia, YU Qiujie. Diffusion weighted imaging combined with magnetic resonance imaging to diagnose the T-staging of rectal cancer [J]. PRACTICAL ONCOLOGY JOURNAL, 2015, 29(5): 400-403.
[3]	XIANG Xueping,TONG Yinghui. Effects of altered metabolic enzymes on epigenetic status in Gliomas [J]. PRACTICAL ONCOLOGY JOURNAL, 2014, 28(4): 371-376.
[4]	QU Ning, LUO Yahong, LI Sen. MRI diagnosis and differential diagnosis of meningioma in lateral ventricle(7cases) [J]. PRACTICAL ONCOLOGY JOURNAL, 2011, 25(2): 141-144.

Functional magnetic resonance imaging in the accurate diagnosis of gliomas

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