新诊断老年多发性骨髓瘤的预后分层及治疗进展

doi:10.11904/j.issn.1002-3070.2022.01.016

Abstract

Abstract: Multiple myeloma(MM)is a malignant proliferative disease of plasma cells that occur in middle-aged and elderly people.It is still incurable.The median diagnostic age is 69 years old,and more than 50% of patients are older than 75 years old at the time of diagnosis.In recent years,the application of new drugs has significantly improved the overall survival and progression-free survival of patients with MM,but the standard regimen does not benefit elderly MM patients,and may also reduce the quality of life and increase mortality.Therefore,the accurate prognostic assessment and risk stratification are essential for individualized treatment.This article reviews the treatment characteristics,prognostic stratification and treatment progress of MM in the elderly.

Key words: Multiple myeloma, Fragility, Elderly assessment, Autologous stem cell transplantation, Adjustment treatment

CLC Number:

R733.3

LI Yujun, LIU Liyang, XIAO Juanjuan, XUE Hua. Prognostic stratification and treatment progress in elderly patients with newly diagnosed multiple myeloma[J]. Journal of Practical Oncology, 2022, 36(1): 84-88.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2022.01.016

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2022/V36/I1/84

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Prognostic stratification and treatment progress in elderly patients with newly diagnosed multiple myeloma

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