外泌体环状RNA在前列腺癌中的研究现状

doi:10.11904/j.issn.1002-3070.2023.01.017

Abstract

Abstract: Circular RNA(circRNA)is a kind of non-coding RNA with covalent closed-loop structure,which can play an important regulatory role in the proliferation,apoptosis,invasion and drug resistance and other biological processes of tumor cells.Exosomes are extracellular vesicles,which participate in material transport and information transmission between cells and can carry a variety of bioactive molecules such as lipids,proteins and nucleic acids.circRNA from the exosomes is enriched and stable in exosomes.circRNA from the exosomes plays an important role in early diagnosis,disease progression and prognosis evaluation of urinary malignant tumors.This article reviews the biological characteristics and functions of circRNA and the research status of exosomal circRNA in prostate cancer.

Key words: Circular RNA, Exosomes, Prostate cancer, Biomarker

CLC Number:

R737.25

LI Hao, TENG Lichen. Research status of exosomal circular RNA in prostate cancer[J]. Journal of Practical Oncology, 2023, 37(1): 92-96.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2023.01.017

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2023/V37/I1/92

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Research status of exosomal circular RNA in prostate cancer

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