蒜素抗肿瘤的研究进展

doi:10.11904/j.issn.1002-3070.2014.06.016

摘要/Abstract

摘要：

蒜素含有丰富的硫化物,具有防治肿瘤、抗菌消炎、预防和治疗心血管疾病、提高机体免疫力等多种生物学功效。研究发现蒜素不仅可以预防多种肿瘤发生,并且对肿瘤有明显的抑制作用,其机制可能与蒜素具有抗氧化作用、降低肿瘤细胞的侵袭力、抑制肿瘤细胞增殖、诱导肿瘤细胞凋亡和直接杀伤肿瘤细胞等作用有关。本文就蒜素抗肿瘤的研究进展进行综述。

关键词: 蒜素, 肿瘤, 细胞周期, 细胞凋亡, 细胞增殖

Abstract:

Allicin,which contains rich sulfide,is provided for prevention and treatment of tumor,anti inflammation,prevention and treatment of cardiovascular diseases,improving immunity and so on.Studies show that allicin can not only prevent many types of cancer,but also has obvious inhibitory effect on tumor.The mechanism is related with antioxidant effects,reducing the invasion of tumor cells,inhibiting the proliferation of tumor cells,inducing tumor cell apoptosis and directly killing the tumor cells.This paper reviews the research progresses on antitumor allicin.

Key words: Allicin, Tumor, Cell cycle, Apoptosis, Cell proliferation

中图分类号:

R979.1

刘跃欣, 周琪, 闫金银综述, 胡万宁审校. 蒜素抗肿瘤的研究进展[J]. 实用肿瘤学杂志, 2014, 28(6): 557-560.

LIU Yuexin,ZHOU Qi,YAN Jinyin,HU Wanning. The research progress on antitumor function of allicin[J]. PRACTICAL ONCOLOGY JOURNAL, 2014, 28(6): 557-560.

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