肿瘤来源微粒在肿瘤发生发展及诊断治疗中的作用

doi:10.11904/j.issn.1002-3070.2015.04.018

实用肿瘤学杂志 ›› 2015, Vol. 29 ›› Issue (4): 368-371.doi: 10.11904/j.issn.1002-3070.2015.04.018

肿瘤来源微粒在肿瘤发生发展及诊断治疗中的作用

陈晓彤,张迎媚综述,周晋审校

哈尔滨医科大学附属第一医院血液内科(哈尔滨 150001)

收稿日期:2015-05-05 出版日期:2015-08-27 发布日期:2015-08-27
通讯作者: 周晋 E-mail:zhoujin1111@126.com
作者简介:陈晓彤,女,(1989-),硕士研究生,从事急性白血病发病机制及治疗方向的研究

The role of tumor derived microparticles in the occurrence,development and diagnosis of tumor

CHEN Xiaotong,ZHANG Yingmei,ZHOU Jin

Department of Hematology and Oncology,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China

Received:2015-05-05 Online:2015-08-27 Published:2015-08-27

摘要/Abstract

摘要： 肿瘤来源微粒(Tumor-derived microparticles,TMPs)是由激活或凋亡的肿瘤细胞释放的直径0.1~1.0μm的细胞外囊泡。它含有其来源细胞的生物活性成分,包括核酸和蛋白质。本文就TMPs在肿瘤发生发展和诊断治疗中作用的研究进展做一综述。

关键词: 肿瘤来源微粒, 肿瘤, 诊断, 进展

Abstract: Tumor derived microparticles are released by activated or apoptotic tumor cells.They are extracellular vesicles which are 0.1~1.0μm in diameters.Tumor derived microparticles carry abundant bioactive molecules,such as nucleic acids and proteins,which resemble that of the parental cell.In this review,we summarize the role of tumor derived microparticles in the occurrence,development,diagnosis and treatment of tumor.

Key words: Tumor derived microparticles, Tumor, Diagnosis, Progress

中图分类号:

R73-3

陈晓彤,张迎媚,周晋. 肿瘤来源微粒在肿瘤发生发展及诊断治疗中的作用[J]. 实用肿瘤学杂志, 2015, 29(4): 368-371.

CHEN Xiaotong,ZHANG Yingmei,ZHOU Jin. The role of tumor derived microparticles in the occurrence,development and diagnosis of tumor[J]. PRACTICAL ONCOLOGY JOURNAL, 2015, 29(4): 368-371.

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肿瘤来源微粒在肿瘤发生发展及诊断治疗中的作用

The role of tumor derived microparticles in the occurrence,development and diagnosis of tumor

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