长链非编码RNAs在口腔鳞癌中的研究进展

doi:10.11904/j.issn.1002-3070.2018.03.014

实用肿瘤学杂志 ›› 2018, Vol. 32 ›› Issue (3): 258-262.doi: 10.11904/j.issn.1002-3070.2018.03.014

长链非编码RNAs在口腔鳞癌中的研究进展

徐文品, 焦琨(综述), 张伟(审校)

吉林大学口腔医学院颌面外科(长春 130021)

收稿日期:2018-03-27 出版日期:2018-07-10 发布日期:2018-07-10
通讯作者: 张伟,E-mail:doctor zhang 888@sina.com
作者简介:徐文品,男,(1991-),硕士研究生,从事口腔颌面外科肿瘤的研究
基金资助:
国家科技计划项目(编号:2016YFC1102805)

Research progress of Long non-coding RNAs in oral squamous cell carcinoma

XU Wenpin,JIAO Kun,ZHANG Wei

Department of Oral and Maxillofacial Surgery,School and Hospital of Stomatology,Jilin University,Changchun 130021,China

Received:2018-03-27 Online:2018-07-10 Published:2018-07-10

摘要/Abstract

摘要： 口腔鳞癌是口腔常见的恶性肿瘤。它具有浸润性生长,区域或远处淋巴转移和预后差的生物学特征。近年来,越来越多的研究发现长链非编码RNAs(Long non-coding RNAs,LncRNAs)在口腔鳞癌中异常表达并调节其生物学行为。本文就长链非编码RNAs在口腔鳞癌中的研究进展做一综述。

关键词: 长链非编码RNA, 口腔鳞癌, 异常表达

Abstract: Oral squamous cell carcinoma is a common malignancy in the oral cavity.It has biological features such as invasive growth,local or distant lymph node metastasis and poor prognosis.In recent years,more and more studies have found that Long non-coding RNAs(LncRNAs)are abnormally expressed in oral squamous cell carcinoma and regulated its biological behavior.This article reviews the research progress of LncRNA in oral squamous cell carcinoma.

Key words: Long non-coding RNAs, Oral squamous cell carcinoma, Aberrant expression

中图分类号:

R739.8

徐文品, 焦琨(综述), 张伟(审校). 长链非编码RNAs在口腔鳞癌中的研究进展[J]. 实用肿瘤学杂志, 2018, 32(3): 258-262.

XU Wenpin, JIAO Kun, ZHANG Wei. Research progress of Long non-coding RNAs in oral squamous cell carcinoma[J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(3): 258-262.

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长链非编码RNAs在口腔鳞癌中的研究进展

Research progress of Long non-coding RNAs in oral squamous cell carcinoma

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