实用肿瘤学杂志 ›› 2018, Vol. 32 ›› Issue (2): 125-129.doi: 10.11904/j.issn.1002-3070.2018.02.007

• 综述 • 上一篇    下一篇

miR-331-3p在恶性肿瘤中的研究进展

李静1, 张云艳2   

  1. 1.哈尔滨医科大学(哈尔滨 150086);
    2.哈尔滨医科大学附属肿瘤医院
  • 收稿日期:2017-10-20 出版日期:2018-04-28 发布日期:2018-05-09
  • 通讯作者: 张云艳,E-mail:Zhangyunyan-1972@163.com
  • 作者简介:李静,女,(1988-),硕士研究生,从事宫颈癌放射治疗的研究。
  • 基金资助:
    国家自然科学基金(编号:8167102096)

Research progress of miR-331-3p in malignant tumors

LI Jing1, ZHANG Yunyan2   

  1. 1.Harbin Medical University,Harbin 150086,China;
    2.Department of Gynecological Radiotherapy,Harbin Medical University Cancer Hospital
  • Received:2017-10-20 Online:2018-04-28 Published:2018-05-09

摘要: miRNA是一种存在于真核生物细胞中的一类内源性非编码的RNA小分子,miR-331-3p作为miRNA家族中的一员,在细胞生理过程中发挥重要作用。近年来,miR-331-3p在恶性肿瘤中的作用日益受到关注。已有研究显示,miR-331-3p在宫颈癌、肝癌、胶质母细胞瘤及前列腺癌等恶性肿瘤的发生发展及复发转移过程中均发挥着重要作用。这些研究结果对恶性肿瘤的诊断及预后起到帮助作用。

关键词: miR-331-3p, 恶性肿瘤, 基因表达

Abstract: miRNA is a small class of endogenous non-coding RNA molecules that exist in eukaryotic cells.miR-331-3p is a member of miRNA family,which plays an important role in the physiological process.In recent years,effects of miR-331-3p on malignant tumors have been increased attention.Studies have demonstrated that miR-331-3p plays an important role in the development,recurrence and metastasis of malignant tumors such as cervical cancer,liver cancer,glioblastoma and prostate cancer.These findings contribute to help the diagnosis and prognosis of malignant tumors.

Key words: miR-331-3p, Malignant tumor, Gene expression

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