2017—2019年深圳市宝安区40~74岁常住居民五癌风险流行状况分析

doi:10.11904/j.issn.1002-3070.2020.04.005

实用肿瘤学杂志 ›› 2020, Vol. 34 ›› Issue (4): 315-320.doi: 10.11904/j.issn.1002-3070.2020.04.005

2017—2019年深圳市宝安区40~74岁常住居民五癌风险流行状况分析

赵仁成¹, 林子棠², 余卫军¹, 雷林³, 刘峥¹, 徐英¹, 郭艳芳¹, 彭绩³

1.深圳市宝安区慢性病防治院(深圳 518100);
2.深圳市龙岗区布吉卫生监督分所;
3.深圳市慢性病防治中心

收稿日期:2020-01-15 发布日期:2020-08-17
通讯作者: 彭绩,E-mail:pengji126@126.com
作者简介:赵仁成,男,(1987-),硕士,主治医师,从事慢性非传染性疾病防治和管理工作的研究。
基金资助:
深圳市宝安区科创局项目(编号:2017JD150);深圳市卫计委项目(编号:SZGW2017009)

Analysis of the prevalence of five cancer risks among permanent residents aged 40~74 years old in Baoan District,Shenzhen,2017—2019

ZHAO Rencheng¹, LIN Zitang², YU Weijun¹, LEI Lin³, LIU Zheng¹, XU Ying¹, GUO Yanfang¹, PENG Ji³

1. Baoan Chronic Diseases Prevention and Cure Hospital,Shenzhen 518100,China;
2. Buji Health Supervision Branch;
3. Shenzhen Centre for Chronic Diseases Prevention and Control

Received:2020-01-15 Published:2020-08-17

摘要/Abstract

摘要： 目的分析深圳市宝安区常住居民“五癌”(肺癌、肝癌、上消化道癌、结直肠癌和乳腺癌)高危人群流行状况,更好地开展高危人群的早期预防、早期诊断和早期治疗工作。方法利用高危人群风险评估模型(由国家癌症中心提供),问卷评估初筛五癌的高危人群,高危人群进一步临床检查。结果 2017—2019年共计完成问卷高危评估6072例,总体癌症高危率为55.55%,肺癌、肝癌、上消化道癌、结直肠癌和女性乳腺癌高危率分别为13.87%、19.60%、25.76%、15.27%和29.77%。单癌种、两癌种、三癌种、四癌种和五癌种高危率分别为31.35%、15.47%、6.19%、2.08%和0.56%。肺癌、肝癌、上消化道癌和结直肠癌高危率均为男性高于女性,差异存在统计学意义(P＜0.05)。肺癌、上消化道癌和结直肠癌在50~69岁年龄段人群高危率较高,肝癌和女性乳腺癌在40~69岁年龄段人群高危率较高,尤其是在40~49岁年龄段最高,总体差异均存在统计学意义(P＜0.01)。疑似肺癌检出率3.16%,肝脏占位阳性率为22.45%,上消化道息肉阳性率为22.09%,大肠癌检出率为0.33%,乳腺BI-RADS3级和BI-RADS4级检出率分别为17.62%和0.82%。结论此分析初步揭示了深圳宝安区的5类癌症的人群高危风险率,阐明了临床筛查依从性和检出率等指标,为进一步优化人群癌症筛查和早诊早治工作提供理论参考。

关键词: 40~74岁, 肺癌, 肝癌, 上消化道癌, 结直肠癌, 乳腺癌, 筛查, 流行状况

Abstract: Objective The aim of this study was to analyze the prevalence of high-risk population of "five cancers"(lung cancer,liver cancer,upper gastrointestinal cancer,colorectal cancer and breast cancer)of permanent residents in Baoan district,Shenzhen,so as to better carry out early prevention,early diagnosis and early treatment work of high-risk populations. Methods The risk assessment model of high-risk groups(provided by the National Cancer Center)was used to evaluate the high-risk groups with five cancers at the initial screening,and the high-risk groups were further clinically examined. Results From 2017 to 2019,a total of 6072 cases were completed.The overall high-risk rate of cancer was 55.55%.The high-risk rates of lung cancer,liver cancer,upper gastrointestinal cancer,colorectal cancer and female breast cancer were 13.87%,19.60%,25.76%,15.27and 29.77%,respectively.The high-risk rates of single cancer species,two cancer species,three cancer species,four cancer species and five cancer species were 31.35%,15.47%,6.19%,2.08% and 0.56%,respectively.The high-risk rates of lung cancer,upper gastrointestinal cancer and colorectal cancer were higher in men than in women,and the differences were statistically significant(P＜0.05).Lung cancer,upper gastrointestinal and colorectal cancer had a higher risk rate among people aged 50~69 years old,and liver cancer and female breast cancer had higher risk rates among people aged 40~69 years old,especially between 40-49 years old highest(P＜0.01).The detection rate of suspected lung cancer was 3.16%,the positive rate of liver occupation was 22.45%,the positive rate of upper gastrointestinal polyps was 22.09%,the detection rate of colorectal cancer was 0.33%,and detection rates of breast BI-RADS3 and BI-RADS4 were 17.62% and 0.82%,respectively. Conclusion This analysis has initially revealed the high-risk rate of the 5 types of cancer population in Baoan district,Shenzhen,and clarified the indicators such as clinical screening compliance and detection rate,providing theoretical reference for further optimization of population cancer screening and early diagnosis and treatment.

Key words: 40~74 years old, Lung cancer, Liver cancer, Upper digestive tract cancer, Colorectal cancer, Breast cancer, Screening, Prevalence

中图分类号:

R73.31

赵仁成, 林子棠, 余卫军, 雷林, 刘峥, 徐英, 郭艳芳, 彭绩. 2017—2019年深圳市宝安区40~74岁常住居民五癌风险流行状况分析[J]. 实用肿瘤学杂志, 2020, 34(4): 315-320.

ZHAO Rencheng, LIN Zitang, YU Weijun, LEI Lin, LIU Zheng, XU Ying, GUO Yanfang, PENG Ji. Analysis of the prevalence of five cancer risks among permanent residents aged 40~74 years old in Baoan District,Shenzhen,2017—2019[J]. Journal of Practical Oncology, 2020, 34(4): 315-320.

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参考文献

1 孙可欣,郑荣寿,张思维,等.2015年中国分地区恶性肿瘤发病和死亡分析[J].中国肿瘤,2019,28(1):1-11.
2 国家卫生和计划生育委员会统计信息中心,中国疾病预防控制中心慢性非传染性疾病预防控制中心.中国死因监测数据集2016[M].北京:中国科学技术出版社,2017.
3 Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015[J].CA Cancer J Clin,2016,66(2):115-132.
4 李诚,兰莉,杨超,等.2015-2017年哈尔滨市恶性肿瘤发病与死亡特征分析[J].实用肿瘤学杂志,2019,33(1):62-66.
5 卫生部疾病预防控制局.癌症早诊早治项目技术方案(2011 年版)[M].北京:人民卫生出版社,2011:8.
6 Zeng H,Chen W,Zheng R,et al.Changing cancer survival in China during 2003-15:a pooled analysis of 17 population-based cancer registries[J].The Lancet Global Health,2018,6(5):555-567.
7 温转,师金,梁迪,等.2018-2019年度河北省城市癌症早诊早治项目人群风险评估分析[J].中国肿瘤,2019,28(10):757-763.
8 张强,黄云超,沈丽达,等.云南省127960名城市居民癌症风险评估及筛查结果分析[J].中国肿瘤,2018,27(9):641-646.
9 Guo L,Zhang S,Liu S,et al.Determinants of participation and detection rate of upper gastrointestinal cancer from population-based screening program in China[J].Cancer Medicine,2019,8(16):7098-7107.
10 王巧燕,彭慧,黄芳,等.上海市嘉定区2013—2017年大肠癌筛查结果分析[J].中国肿瘤,2018,27(9):647-651.
11 张峰,王卫国,谢燕,等.松江区居民大肠癌筛查及检查顺应性的影响因素分析[J].浙江预防医学,2015,27(1):17-20.
12 关政,张爱莲.2015年山西省晋城市五大类癌症高风险人群调查结果分析[J].中国药物与临床,2017,17(9):1317-1319.
13 代敏,李霓,李倩,等.中国肿瘤预防控制概况[J].中国肿瘤,2011,20(12):868-873.
14 师金,梁迪,李道娟,等.全球女性乳腺癌流行情况研究[J].中国肿瘤,2017,26(9):683-690.
15 Ji M,Liu Z,Chang ET,et al.Mass screening for liver cancer:results from a demonstration screening project in Zhongshan City,China[J].Scientific Reports,2018,8(1):1-10.
16 陈万青,李霓,石菊芳,等.中国城市癌症早诊早治项目进展[J].中国肿瘤,2019,28(1):23-25.
17 Siegel RL,Miller KD,Jemal A.Cancer statistics,2020[J].CA Cancer J Clin,2020,0(0):1-24.

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2017—2019年深圳市宝安区40~74岁常住居民五癌风险流行状况分析

Analysis of the prevalence of five cancer risks among permanent residents aged 40~74 years old in Baoan District,Shenzhen,2017—2019

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